实用妇产科杂志2024，Vol.40Issue(11)：905-911,7.
产前和产后HELLP综合征的临床特征以及妊娠结局分析
Analysis of Clinical Features and Pregnancy Outcomes of Antenatal and Post-natal HELLP Syndrome
摘要
Abstract
Objective:The clinical characteristics of pregnant women with HELLP syndrome before and after delivery and the risk factors of pregnancy outcomes were analyzed.Methods:A retrospective analysis was con-ducted on 126 cases of HELLP syndrome admitted to The Affiliated Suzhou Hospital of Nanjing Medical University from January 2010 to May 2021,divided into prenatal HELLP group[n=108,98 cases with severe preeclampsia(SPE)]and postpartum HELLP group(n=18,15 cases with SPE),to compare the differences in clinical charac-teristics and pregnancy outcomes between the two groups with the different onset time and whether they were complicated with SPE.Results:①Compared with the postpartum HELLP group,the prenatal HELLP group had higher systolic blood pressure in the third trimester of pregnancy,shorter time from preeclampsia to HELLP syn-drome,higher liver function abnormalities,lower platelet counts,and lower 24-hour urinary protein,with statistically significant differences(P＜0.05).There was no statistically significant differences in adverse pregnancy outcomes and neonatal prognosis between the two groups(P＞0.05).②When combined with SPE,the antenatal HELLP group had a shorter interval from preeclampsia to HELLP syndrome,lower platelet counts,and higher liver en-zymes than the postpartum HELLP group,with statistically significant differences(P＜0.05).③There was no sig-nificant difference in clinical features between the antenatal HELLP group and the postpartum HELLP group when not complicated with SPE(P＞0.05).Conclusions:There is only one difference between prenatal and postnatal HELLP syndrome in terms of the speed of disease progression,the time taken from preeclampsia to HELLP syn-drome,and both can lead to serious maternal and neonatal complications,which should be identified early in clini-cal practice.关键词
HELLP综合征/子痫前期/妊娠结局/影响因素Key words
HELLP syndrome/Preeclampsia/Pregnancy outcome/Influencing factors分类
医药卫生引用本文复制引用
李维,周丽屏,康苏娅..产前和产后HELLP综合征的临床特征以及妊娠结局分析[J].实用妇产科杂志,2024,40(11):905-911,7.基金项目
江苏省妇幼健康科研项目(编号:F202045) （编号:F202045）
苏州市"临床医学专家团队"引进项目(编号:SZYJTD201709) （编号:SZYJTD201709）
