同位素2024，Vol.37Issue(6)：507-520,14.DOI:10.7538/tws.2024.youxian.100
加速器生产重要医用放射性同位素及应用概况
Progress in Accelerator Production of Important Medical Isotopes
摘要
Abstract
With the rapid development of nuclear science and technology,medical radioisotopes play an increasingly important role in nuclear medicine,and are widely used in the diagnosis and treatment of cardiovascular and cerebrovascular diseases,tumors and other diseases.Accelerator production of medical radioisotopes has the advantages of flexibility,efficiency,system safety and high nuclide activity,and is one of the important production methods to ensure the safe and stable supply of medical radioisotopes.In 2021,China Atomic Energy Authority together with seven other ministries,jointly released the"Medium-and Long Term Development Plan for Medical Isotopes(2021-2035)",which clarifies that there are 14 important medical isotopes that China needs to focus on developing before 2035,of which 9 isotopes can be produced by accelerators.This article mainly introduces the production and application overview of accelerators for the 9 important medical isotopes listed in the plan.The 9 important medical isotopes include the imaging nuclides 123I,124I,64Cu,68Ga,89Zr and the therapeutic nuclides 186Re,103Pd,225Ac,223Ra.Among them,225Ac、68Ge and 223Ra are the focus of isotope production in medium and high energy accelerators,and also are the main development trend of accelerator production radioisotopes.This study provides a comprehensive review of the nuclear properties,applications,reaction cross-sections,yields,and production methods of the diagnostic and therapeutic nuclides mentioned above,providing reference for the production of related nuclides.关键词
加速器/医用同位素生产/显像核素/治疗核素Key words
accelerator/medical isotope production/imaging nuclides/therapeutic nuclides分类
能源科技引用本文复制引用
安世忠,官国英,赵云龙,王哲,李勇,王宇,赵鹏飞,宋国芳,王国宝..加速器生产重要医用放射性同位素及应用概况[J].同位素,2024,37(6):507-520,14.基金项目
国防科工局"核能开发"科研项目(HNKF202221(36)) （HNKF202221(36）
国家自然科学基金(12375156) （12375156）
