临床医学工程2024，Vol.31Issue(12)：1501-1502,2.DOI:10.3969/j.issn.1674-4659.2024.12.1501
依折麦布联合奥扎格雷钠对进展性缺血性脑卒中患者神经功能及血管内皮功能的影响
Impact of Ezetimibe Combined with Ozagrel Sodium on Neurological Function and Vascular Endothelial Function of Patients with Progressive Ischemic Stroke
王苗苗 1薛文俊 1高延伦 1冯校迅1
作者信息
- 1. 平顶山市第一人民医院神经内科二病区,河南 平顶山 467000
- 折叠
摘要
Abstract
Objective To explore the clinical effect of ezetimibe combined with ozagrel sodium in the treatment of progressive ischemic stroke(PIS).Methods 116 patients with PIS were randomly divided into two groups.The reference group was treated with ozagrel sodium,and the combined group was treated with ezetimibe combined with ozagrel sodium.The neurological function,vascular endothelial function and adverse reactions were compared between the two groups.Results After 14 days of treatment,the NIHSS score and serum ET-1 level of the combined group were lower than those of the reference group,and the serum eNOS and NO levels were higher than those of the reference group(P<0.05).Conclusions Ezetimibe combined with ozagrel sodium in the treatment of PIS can significantly reduce the damage of vascular endothelial function and improve the neurological function of patients,with high safety.关键词
依折麦布/奥扎格雷钠/进展性缺血性脑卒中/神经功能/血管内皮功能Key words
Ezetimibe/Ozagrel sodium/Progressive ischemic stroke/Neurological function/Vascular endothelial function分类
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王苗苗,薛文俊,高延伦,冯校迅..依折麦布联合奥扎格雷钠对进展性缺血性脑卒中患者神经功能及血管内皮功能的影响[J].临床医学工程,2024,31(12):1501-1502,2.
