临床医学工程2024,Vol.31Issue(12):1565-1566,2.DOI:10.3969/j.issn.1674-4659.2024.12.1565
卵巢癌组织SIRT-1、PLAGL2表达与患者临床病理参数及预后的关系分析
Analysis on the Relationships of SIRT-1 and PLAGL2 Expressions in Ovarian Cancer Tissue with the Clinical Pathological Parameters and Prognosis of Patients
宋晓娜 1卫兰 1杨文君1
作者信息
- 1. 三门峡市中心医院病理科,河南 三门峡 472000
- 折叠
摘要
Abstract
Objective To analyze the relationships of SIRT-1 and PLAGL2 expressions in ovarian cancer tissue with the clinical pathological parameters and prognosis of patients.Methods 76 patients with ovarian cancer were selected,and the relationships of SIRT-1 and PLAGL2 expressions in cancer tissue with the clinical pathological parameters and prognosis were analyzed.Results Cox analysis showed that FIGO stageⅢ~Ⅳ,low differentiation,lymph node metastasis,and positive expressions of SIRT-1 and PLAGL2 were independent influencing factors for the prognosis of patients with ovarian cancer(P<0.05).Conclusions The positive expression rates of SIRT-1 and PLAGL2 increase significantly in ovarian cancer tissue,and their expressions are related to the clinical pathological parameters and prognosis.关键词
卵巢癌/SIRT-1/PLAGL2/临床病理参数/预后Key words
Ovarian cancer/SIRT-1/PLAGL2/Clinical pathological parameter/Prognosis分类
医药卫生引用本文复制引用
宋晓娜,卫兰,杨文君..卵巢癌组织SIRT-1、PLAGL2表达与患者临床病理参数及预后的关系分析[J].临床医学工程,2024,31(12):1565-1566,2.