磁共振成像2024，Vol.15Issue(11)：90-95,6.DOI:10.12015/issn.1674-8034.2024.11.014
表观扩散系数在预测肝泡状棘球蚴病发生远处转移的临床价值
Clinical value of apparent diffusion coefficient in predicting distant metastasis in hepatic alveolar echinococcosis
摘要
Abstract
Objective:To explore the clinical value of apparent diffusion coefficient(ADC)in predicting distant metastasis of hepatic alveolar echinococcosis(HAE).Materials and Methods:A retrospective analysis was conducted on 267 patients diagnosed with HAE at Qinghai University Affiliated Hospital from January 2019 to March 2024,including 88 cases with distant metastasis and 179 cases without metastasis.Clinical and imaging information was recorded,and the maximum apparent diffusion coefficient(ADCmax),minimum apparent diffusion coefficient(ADCmin),and mean apparent diffusion coefficient(ADCmean)of the solid part and peripheral zone of the lesions were measured on diffusion-weighted imaging(DWI).Statistical methods were used to compare the differences between patients with distant metastasis and those without metastasis in terms of age,sex,ethnicity,ADCmax,ADCmin,and ADCmean of the solid part and peripheral zone of the lesions.Receiver operating characteristic(ROC)curves were plotted,and the area under the curve(AUC)was calculated to evaluate the diagnostic performance of each parameter.The optimal diagnostic cutoff values and their corresponding sensitivities and specificities were calculated.Results:There were no statistically significant differences in age,sex,or ethnicity between the group with distant metastasis of HAE and the group without metastasis(P＞0.05).Regarding the solid part of the lesions,there were no significant differences in ADCmax,ADCmin,or ADCmean between the group with distant metastasis and the group without metastasis(P＞0.05).However,significant differences in ADCmax,ADCmin,and ADCmean were observed between the two groups in the peripheral zone of the lesions(P＜0.05).Additionally,regardless of metastasis occurrence,ADCmax,ADCmin,and ADCm an in the peripheral zone were lower than those in the solid component.ROC curve analysis demonstrated that ADC values in the peripheral zone could effectively predict distant metastasis of HAE.Among them,the combined index showed the best efficacy in predicting distant metastasis of HAE,the AUC is 0.955(95％CI:0.923-0.977),with a sensitivity of 93.2％and a specificity of 86.0％.Conclusions:The ADC values in the peripheral zone have good predictive value for assessing whether HAE will develop distant metastasis in the clinical setting.The combined use of various parameters can further enhance the predictive efficacy of distant metastasis in HAE,facilitating the realization of individualized and precise medical decision-making.关键词
肝泡状棘球蚴病/远处转移/边缘带/表观扩散系数/磁共振成像Key words
hepatic alveolar echinococcosis/distant metastasis/peripheral zone/apparent diffusion coefficient/magnetic resonance imaging分类
医药卫生引用本文复制引用
丹增耶昂,鲍海华,张雪倩,龙昌友,邢玉洁,田鹏启..表观扩散系数在预测肝泡状棘球蚴病发生远处转移的临床价值[J].磁共振成像,2024,15(11):90-95,6.基金项目
国家临床重点专科建设项目(编号:青卫健办[2024]90号) National Clinical Key Specialty Construction Project[No.Qing Wei Jian Ban(2024)90] （编号:青卫健办[2024]90号）
