广东医学2024,Vol.45Issue(12):1544-1548,5.DOI:10.13820/j.cnki.gdyx.20241595
间充质干细胞治疗在肺动脉高压中的研究进展
Research progress of mesenchymal stem cell therapy in pulmonary hypertension
摘要
Abstract
Pulmonary hypertension(PH)is a clinical pathophysiological syndrome characterized by a progressive increase in pulmonary vascular resistance and is often associated with various disease complications.Mesenchymal stem cells(MSCs)possess unique properties,including the ability to home to damaged tissues,repair functionality,and par-ticipate in the regulation of systemic inflammation and immune responses,making them a promising candidate for clinical applications.This article reviews recent preclinical studies on the application of MSCs in the treatment of pulmonary hyper-tension,aiming to provide scientific evidence for future clinical practices.关键词
肺动脉高压/间充质干细胞/外囊泡Key words
pulmonary hypertension/mesenchymal stem cells/extracellular vesicles分类
医药卫生引用本文复制引用
董志会,饶墅科,谢衬梨,徐桂华..间充质干细胞治疗在肺动脉高压中的研究进展[J].广东医学,2024,45(12):1544-1548,5.基金项目
国家自然科学基金资助项目(81960427) (81960427)
东莞市社会发展科技项目(20221800905222、20221800905212、20231800935542) (20221800905222、20221800905212、20231800935542)