吉林农业大学学报2024，Vol.46Issue(6)：971-978,8.DOI:10.13327/j.jjlau.2024.0678
磁性灵芝孢子的制备及其缓释性能研究
Preparation and Sustained-release Properties of Magnetic Gano-derma Lucidum Spores
摘要
Abstract
Using natural polymer material Ganoderma lucidum spores(GLS)as the template,after treatment with acetone degreasing,potassium hydroxide solution and orthophosphoric acid solution,it was found that the pores in the outer wall of GLS become more and larger.From the SEM images,it was observed that the inner wall was flat and smooth,and formed internal and external channels.Then,Fe3O4 nanoparticles were deposited by chemical coprecipitation method,and the prepared MGLS was analyzed by a series of characterization methods.The in vitro release process of MGLS loaded with Rhodamine B(RhB)was investigated.It was found that at 6,24 and 48 hours of testing,the cumulative release reached 47.3%,88.4%and 92.3%,respectively.The results show that MGLS,as a drug delivery carrier,has a significant sustained-release effect on RhB.关键词
灵芝孢子/Fe3O4纳米粒子/表征分析/罗丹明B/缓释性能Key words
Ganoderma lucidum spore/Fe3O4 nanoparticle/characterization analysis/rhodamine B/sustained release property分类
农业科技引用本文复制引用
陈玉宁,申晓彤,韩斌,李景梅..磁性灵芝孢子的制备及其缓释性能研究[J].吉林农业大学学报,2024,46(6):971-978,8.基金项目
吉林省发展和改革委员会项目(2022C039-5) （2022C039-5）
