基础医学与临床2025，Vol.45Issue(1)：98-101,4.DOI:10.16352/j.issn.1001-6325.2025.01.0098
高龄多发性骨髓瘤鞍区占位1例
Sellar multiple myeloma in an elderly patient:a case report
摘要
Abstract
Objective To investigate the clinical characteristics in an elderly patient with sellar multiple myeloma.Methods Clinical features,laboratory data and radiologic profile of an elderly patient with sellar multiple myeloma were collected.Results The patient was an 85-year-old male.The main clinical manifestations were fatigue,poor appetite and polyuria.Laboratory examinations showed a significant decrease in blood sodium,several anterior pitu-itary hormones and an increase in total protein,mass of pituitary lesion and concentration of prolactin.During etio-logical screening,it was found that the blood immunoglobulin G(IgG)level was significantly increased,the blood M protein was positive and the bone marrow smear showed myeloma cells accompanied by multiple osteolytic lesions in the bones of the whole body.Considering the diagnosis of multiple myeloma,the pituitary lesion was likely to be the extra-medullary involvement.Conclusions The intrasellar plasmacytoma is not common.The disease onset is insidious with clinical features and imaging findings lacking specificity.Therefore,diagnosis relies on biopsy which poses risks for elderly patients and increases diagnostic challenges leading to misdiagnosis.关键词
多发性骨髓瘤/鞍区占位/鞍内浆细胞瘤/高龄Key words
multiple myeloma/sellar lesion/intrasellar plasmacytoma/elderly分类
医药卫生引用本文复制引用
陈晓雪,段炼,柯晓安,阳洪波,潘慧,朱惠娟,王林杰..高龄多发性骨髓瘤鞍区占位1例[J].基础医学与临床,2025,45(1):98-101,4.基金项目
中央高水平医院临床科研业务费资助(2022-PUMCH-A-064) （2022-PUMCH-A-064）
