基础医学与临床2025，Vol.45Issue(1)：116-120,5.DOI:10.16352/j.issn.1001-6325.2025.01.0116
鉴别肺孢子菌感染与定植的研究进展
Progress of researches on the differential diagnosis of Pneumocystis jiroveci infection and colonization
摘要
Abstract
Pneumocystis jiroveci(PJ)is an atypical conditional pathogenic fungus.PJ colonization is a potential risk factor for Pneumocystis jiroveci pneumonia(PJP).Active identification of PJ colonization or infection is conducive to rational use of antibiotics.Although serum G test combined with molecular detection technology,peripheral blood CD4+T level and independent characterization of trophozoites and cysts by transcriptome sequencing technology may support identifying PJ colonization and diagnosis of infection,unified standards have not yet been established.Based on the pathogenic characteristics and pathogenic mechanism of PJ,clinical characteristics and diagnostic methods of PJP,this paper reviews the progress of differential diagnosis of PJ infection and colonization,so as to provide more objective and comprehensive differential strategy for clinical diagnosis and treatment.关键词
耶氏肺孢子菌/肺孢子菌肺炎/定植/诊断/鉴别诊断Key words
Pneumocystis jroveci/Pneumocystis jroveci pneumonia/colonization/diagnosis/differential diagnosis分类
临床医学引用本文复制引用
李星辰,童瑾..鉴别肺孢子菌感染与定植的研究进展[J].基础医学与临床,2025,45(1):116-120,5.基金项目
2022年度重庆市卫生适宜技术推广项目(2022jstg021) （2022jstg021）
