不同非药物干预措施改善乳腺癌患者疲乏效果的网状Meta分析OACSTPCD

Objective To evaluate and compare the efficacy of different non-drug interventions on cancer-related fatigue in breast cancer patients,and to provide evidence for the formulation of relevant intervention programs.Methods We systematically retrieved randomized controlled trials(RCT)on the effects of non-drug interventions on cancer-related fatigue in breast cancer patients from CNKI,Wanfang Data,VIP,CBM,Medline,PubMed,Web of Science,the Cochrane Library.The retrieval period spanned from the inception to August 2024.Stata14.0 was used for data analysis.Results A total of 38 studies were included,including 12 non-pharmaceutical interventions,involving 3 901 breast cancer patients.The results showed that compared with conventional care,resistance and high-intensity interval training,aerobic and high-intensity interval exercise,cognitive behavioral therapy,yoga and massage had better effects on cancer-related fatigue in breast cancer patients(P<0.05).The area under the cumulative rank probability map showed that resistance and high-intensity interval training was the best non-drug intervention.Conclusion A combination of resistance exercise and high-intensity interval training is the most effective for alleviating fatigue in breast cancer patients,and it is recommended that clinical nursing prioritize this approach.However,a large number of high-quality RCTs are still needed for the verification.