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子宫内膜癌患者生育力保留的最佳证据总结OACSTPCD

Summary of the Best Evidence for Fertility Preservation in Patients with Endometrial Cancer

中文摘要英文摘要

目的:系统检索、评价和总结子宫内膜癌患者生育力保留的最佳证据,为医护人员对子宫内膜癌患者进行生育力保留治疗提供理论依据.方法:依据"6S"证据模型,系统检索国内外数据库、各指南及专业协会网站中有关子宫内膜癌患者生育力保留的相关文献,包括指南、证据总结、推荐实践、系统评价和专家共识.检索时限为建库至2023年12月.结果:共纳入13篇文献,包括临床决策4篇、指南2篇、系统评价3篇、专家共识4篇,从多学科团队管理、生育咨询、适用及禁用人群、治疗前评估、治疗方式、助孕策略、围产期管理、随访指导、终止标准、预防复发10个方面汇总了 30条证据.结论:子宫内膜癌患者生育力保留的最佳证据为医护人员对子宫内膜癌患者进行生育力保留治疗提供了循证依据.医护人员在证据应用时,需根据患者的肿瘤治疗情况,结合患者的生育意愿制定个体化的生育力保留治疗方案.

Objective:To systematically search,evaluate and summarize the best evidence of fertility preservation in pa-tients with endometrial cancer,and provide a theoretical basis for medical staff to carry out fertility-sparing treatment in pa-tients with endometrial cancer.Methods:According to the'6S'evidence model,literature on fertility preservation in pa-tients with endometrial cancer was systematically searched from domestic and foreign databases,guidelines and professional association websites,including guidelines,evidence summary,recommended practice,systematic review and expert consen-sus.The publication date is up to December 2023.Results:A total of 13 articles were included,including 4 clinical deci-sions,2 guidelines,3 systematic reviews and 4 expert consensus.30 pieces of evidence were summarized from 10 aspects,in-cluding multidisciplinary team management,fertility consultation,applicable population,evaluation before treatment,treatment methods,pregnancy assistance strategies,perinatal management,follow-up guidance,termination crite-ria and recurrence prevention.Conclusion:The best evidence of fertility preservation in patients with endometrial cancer provides evidence for medical staff to carry out fertility preservation therapy in patients with endometrial cancer.In the application of evidence,medical staff should formulate an individualized fertility preservation treatment plan according to the patient s tumor treatment and the patient's fertility intention.

廖疏影;蒋红梅;刘颖;曾裕;江庆华

610500 成都,成都医学院护理学院610500 成都,成都医学院护理学院610500 成都,成都医学院护理学院610500 成都,成都医学院护理学院610041 成都,四川省肿瘤临床医学研究中心,四川省肿瘤医院·研究所,四川省癌症防治中心,电子科技大学附属肿瘤医院放疗中心

临床医学

子宫内膜癌生育力保留生育护理证据总结循证护理

Endometrial cancerFertility preservationFertility careSummary of evidenceEvidence-based nursing

《肿瘤预防与治疗》 2024 (12)

1035-1043,9

This study was supported by grants from Science and Technology Department of Sichuan Province(No.2020YFS0411). 四川省科技厅2020年度社会发展领域重点研发项目(编号:2020YFS0411)

10.3969/j.issn.1674-0904.2024.12.003

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