同济大学学报（医学版）2024，Vol.45Issue(6)：811-817,7.DOI:10.12289/j.issn.2097-4345.24046
全身炎症反应指数对下肢股腘动脉闭塞介入术后的预后评估价值
Systemic inflammatory response index for predicting outcomes of interventional surgery in patients with femoral popliteal artery occlusion
摘要
Abstract
Objective To explore preoperative systemic inflammatory response index(SIRI)in predicting outcomes of intraluminal surgery in patients with femoral popliteal artery occlusion of the lower limbs.Methods A total of 227 patients with femoral popliteal artery occlusion who underwent intraluminal interventional surgery in two medical centers from January 2019 to December 2022 were enrolled.Preoperative SIRI values were calculated and patients were stratified into three groups according to SIRI tertiles.The primary endpoint of the study was unplanned reintervention and the secondary endpoint was compound adverse events,including all-cause death and surgical amputation of the affected limb.Results Patients were followed up for one year after surgical intervention.During the follow-up period the unplanned reintervention was performed in 60 cases,and adverse events occurred in 85 cases.Kaplan-Meier analysis demonstrated that patients with upper tirtile SIRI exhibited significantly higher rates of unplanned reintervention and incidence of compound adverse events(P＜0.01).Univariate and multivariate COX analyses showed that higher SIRI value as a continuous variable or categorical variable was an independent risk factor for unplanned reintervention(HR=1.278,95％CI:1.081-1.511,P=0.04;HR=2.849,95％CI:1.430-5.678,P=0.03).Conclusion SIRI is an independent risk factor for clinical reintervention,which may serve as a predictor for outcomes of interventional surgery in patients with femoral popliteal artery occlusion.关键词
全身炎症反应指数/下肢动脉硬化闭塞症/股胭动脉闭塞/腔内介入治疗/预后Key words
systemic inflammatory response index/lower extremity arteriosclerosis obliterans/femoropopliteal arteryocclusion/intracavitary interventional therapy/prognosis分类
医药卫生引用本文复制引用
彭彦蓉,雍熙,朱江,李大志,何智涛,郑江华..全身炎症反应指数对下肢股腘动脉闭塞介入术后的预后评估价值[J].同济大学学报（医学版）,2024,45(6):811-817,7.基金项目
国家自然科学基金项目培育专项(20SXZRKX00009) （20SXZRKX00009）
