肿瘤预防与治疗2024,Vol.37Issue(12):1076-1083,8.DOI:10.3969/j.issn.1674-0904.2024.12.009
放疗联合免疫治疗在局部晚期不可切除食管癌中的研究进展
Research Progress of Radiotherapy Combined with Immunotherapy in the Treatment of Locally Advanced Unresectable Esophageal Cancer
摘要
Abstract
With the emergence of immunotherapy,the treatment of esophageal cancer has been undergoing a profound transformation.Currently,immunotherapy is recommended as the first-line therapy for advanced esophageal cancer.However,for patients with locally advanced and unresectable esophageal cancer,the current standard treatment remains radical radio-therapy combined with chemotherapy,often resulting in unfavorable prognosis.Nevertheless,accumulating evidence suggests that the combination of radiotherapy and immunotherapy can yield synergistic effects.This article aims to comprehensively re-view the underlying mechanisms of this combined approach and its clinical applications in the management of locally ad-vanced and unresectable esophageal cancer.关键词
食管癌/放疗/免疫治疗/局部晚期/不可切除/研究进展Key words
Esophageal cancer/Radiotherapy/Immunotherapy/Locally advanced/Unresectable/Research progress分类
医药卫生引用本文复制引用
谢良云,张志..放疗联合免疫治疗在局部晚期不可切除食管癌中的研究进展[J].肿瘤预防与治疗,2024,37(12):1076-1083,8.基金项目
This study was supported by Natural Science Foundation of Hebei Province(No.H2023105018). 河北省自然科学基金(编号:H2023105018) (No.H2023105018)