首页|期刊导航|同济大学学报(医学版)|FGR妊娠母体眼动脉多普勒超声参数及视神经鞘宽度变化与新生儿出生体重的关系

FGR妊娠母体眼动脉多普勒超声参数及视神经鞘宽度变化与新生儿出生体重的关系OACSTPCD

Ultrasound Doppler parameter changes of ocular artery and optic nerve sheath width in pregnant women with fetal growth restriction

中文摘要英文摘要

目的 探讨胎儿生长受限(fetal growth restriction,FGR)妊娠母体眼动脉超声多普勒参数和视神经鞘宽度的变化特征,及其与新生儿出生体重的相关性.方法 纳入2022年7月-2023年4月同济大学附属妇产科医院建卡产检的FGR孕妇20例及相匹配的正常孕妇30例,对比两组孕妇一般情况、妊娠结局、眼动脉多普勒参数及视神经鞘宽度的变化特征,收缩期峰值流速比值(peak ratio,PR)与新生儿出生体重的相关性.结果 正常孕妇组和FGR孕妇组左、右眼动脉间各参数比较差异均无统计学意义(P>0.05).FGR孕妇组眼动脉PR值较正常孕妇组明显增大;轻度FGR孕妇组视神经鞘宽度较重度组明显增加,差异均有统计学意义,PR值与新生儿出生体重呈负相关(P<0.01),其他眼动脉超声多普勒参数差异均无统计学意义.结论 FGR孕妇组眼动脉PR值明显上升,PR值与新生儿出生体重呈负相关,PR值有望成为提示FGR胎儿及其不良预后的可用指标.

Objective To investigate the association of ultrasound Doppler parameter changes of ocular artery and optic nerve sheath width in fetal growth restriction(FGR)pregnant women with birth weight of newborns.Methods Twenty pregnant women with FGR and 30 matched normal pregnant women were enrolled in Shanghai First Maternal and Infant Health Hospital from July 2022 to April 2023.Ultrasonography was performed in both groups,the general conditions,pregnancy outcomes,ocular artery Doppler parameters and optic nerve sheath width were compared between two groups.The association of maternal ophthalmal artery Doppler parameters and optic nerve sheath width with birth weight of newborns was analyzed.Results The ocular artery peak ratio(PR)value of FGR pregnant women was significantly higher than that of normal pregnant women,and the optic nerve sheath width in the mild FGR group was significantly higher than that in the severe FGR group;and the PR value was negatively correlated with the birth weight of newborns(P<0.01).Conclusion The PR value of the ocular artery in pregnant women with FGR is significantly increased,suggesting that PR value mignt be used as an indicator for FGR and birth outcomes for pregnant women.

陈蕴琪;吕小利;胡丹;杨丽娟;任敏

同济大学附属妇产科医院超声科,上海 201204同济大学附属妇产科医院超声科,上海 201204同济大学附属妇产科医院超声科,上海 201204同济大学附属妇产科医院超声科,上海 201204同济大学附属妇产科医院超声科,上海 201204

临床医学

眼动脉多普勒超声胎儿生长受限

ophthalmic arteryDoppler ultrasoundfetal growth restriction

《同济大学学报(医学版)》 2024 (6)

845-850,6

国家重点研发计划(2022YFC2704700)

10.12289/j.issn.2097-4345.24039

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