粪菌移植治疗炎症性肠病躯体-心理症状的研究进展OACSTPCD

Inflammatory bowel disease(1BD)is a chronic non-specific intestinal inflammatory disorder mediated by immunity disturbance with increasing incidence recently.Studies have shown that IBD not only affects the normal functions of the digestive system but also has an impact on mental and behavioral functions of patients through the microbiota-gut-brain axis.Psychological comorbidities such as anxiety and depression have a particularly prominent effect on IBD patients.Additionally,the interactions between the gut and psychological factors can also influence the natural course of the disease and increase the risk of adverse outcomes.Therefore,alongside the treatment of the physical symptoms of IBD,the psychological interventions have received more and more attentions.Fecal microbiota transplantation therapy has been emerged as a treatment strategy based on the concept of microbiota-gut-brain axis.This article provides a review of the interaction between the physical and psychological symptoms of IBD and explores the potential application of fecal microbiota transplantation in treatment of phychosomatic symptoms in IBD.