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多个CT征象单独及联合应用在甲状腺滤泡癌与滤泡性腺瘤鉴别诊断中的价值

林婵君 陈夏浦 郑旭峰 孙建鸿 林黛英 马树华

汕头大学医学院学报2024,Vol.37Issue(4):207-211,5.
汕头大学医学院学报2024,Vol.37Issue(4):207-211,5.DOI:10.13401/j.cnki.jsumc.2024.04.003

多个CT征象单独及联合应用在甲状腺滤泡癌与滤泡性腺瘤鉴别诊断中的价值

The value of multiple CT signs alone and in combination in the differential diagnosis of thyroid follicular carcinoma and follicular adenoma

林婵君 1陈夏浦 2郑旭峰 2孙建鸿 3林黛英 2马树华4

作者信息

  • 1. 汕头大学医学院第一附属医院放射科,广东 汕头 515041||汕头市中心医院放射科,广东 汕头 515041
  • 2. 汕头市中心医院放射科,广东 汕头 515041
  • 3. 汕头市中心医院病理科,广东 汕头 515041
  • 4. 汕头大学医学院第一附属医院放射科,广东 汕头 515041
  • 折叠

摘要

Abstract

Objective:To investigate the value of multiple CT signs alone and in combination in the differential diagnosis of follicular thyroid carcinoma(FTC)and follicular thyroid adenoma(FTA).Methods:31 patients with FTC and 69 patients with FTA who underwent neck CT at Shantou Central Hospital from February 2019 to May 2024 and were diagnosed by postoperative histopathology were retrospectively included.The differences in CT signs(including four types of localized protrusion,eggshell-like calcification,multi-nodule sign,and border blurring)between the two groups were compared.Postoperative pathologic findings were used as the gold standard to compare the diagnostic efficacy of the four CT signs alone and in combination for FTC.Results:Compared with FTA,all 4 CT signs,including localized protrusion,eggshell-like calcification,multi-nodule sign,and border blurring,were more common in FTC(all P<0.05).Among the single CT signs,localized protrusion had the greatest diagnostic value,with a sensitivity,specificity,and accuracy of 67.7%,97.1%,and 88%,respectively;in the combined diagnosis of the 2 CT signs,the specificity of localized protrusion+any of the other signs was 100%,and localized protrusion+border blurring had the highest sensitivity,specificity,and accuracy,with 45.1%,100%,and 83%,respectively;and the sensitivity,specificity,and accuracy of the combined diagnosis of the 3 CT signs were highest for localized protrusion+eggshell-like calcification+border blurring,with 32.2%,100%,and 79%,respectively;and for the combined diagnosis of the 4 CT signs,the sensitivity,specificity,and accuracy were 3.2%,100%,and 70%,respectively.Conclusion:Localized protrusion has a high differential diagnostic value for FTC and FTA,while multiple CT signs combined can improve diagnosis specificity.

关键词

甲状腺滤泡癌/甲状腺滤泡性腺瘤/鉴别诊断/体层摄影术,X线计算机

Key words

follicular thyroid carcinoma/follicular thyroid adenoma/differential diagnosis/tomography,X-ray computed

分类

医药卫生

引用本文复制引用

林婵君,陈夏浦,郑旭峰,孙建鸿,林黛英,马树华..多个CT征象单独及联合应用在甲状腺滤泡癌与滤泡性腺瘤鉴别诊断中的价值[J].汕头大学医学院学报,2024,37(4):207-211,5.

基金项目

汕头市医疗卫生科技计划(230509116495613) (230509116495613)

汕头大学医学院学报

1007-4716

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