首页|期刊导航|医学信息|白细胞介素-11联合生血宝治疗恶性肿瘤化疗后血小板减少的疗效观察

白细胞介素-11联合生血宝治疗恶性肿瘤化疗后血小板减少的疗效观察OA

Observation on the Curative Effect of Interleukin-11 Combined with Shengxuebao in the Treatment of Thrombocytopenia After Chemotherapy for Malignant Tumors

中文摘要英文摘要

目的 探讨白细胞介素-11 联合生血宝治疗恶性肿瘤化疗后血小板减少的疗效.方法 选取 2019 年 1 月-2023 年 10 月宜丰县人民医院收治的 60 例恶性肿瘤患者为研究对象,按照随机数字表法分为研究组和对照组,各 30 例.对照组患者采用白细胞介素-11 治疗,研究组患者采用白细胞介素-11 联合生血宝治疗.比较两组临床疗效、血小板减少症发生率、血小板计数(PC)及血小板计数变化情况.结果 研究组治疗总有效率高于对照组(P<0.05);研究组血小板减少症发生率低于对照组(P<0.05);两组治疗后PC水平高于治疗前,且研究组PC水平高于对照组(P<0.05).研究组血小板计数<50×109/L持续时间、恢复至 70×109/L所需时间、恢复至 100×109/L所需时间均短于对照组(P<0.05).结论 白细胞介素-11 联合生血宝治疗恶性肿瘤化疗后血小板减少的效果确切,能够更有效预防恶性肿瘤化疗后血小板减少症,缩短患者血小板计数恢复正常时间.

Objective To investigate the efficacy of interleukin-11 combined with Shengxuebao in the treatment of thrombocytopenia after chemotherapy for malignant tumors.Methods A total of 60 patients with malignant tumors admitted to Yifeng County People's Hospital from January 2019 to October 2023 were selected as the research objects.According to the random number table method,they were divided into study group and control group,with 30 patients in each group.The control group was treated with interleukin-11,and the study group was treated with interleukin-11 combined with Shengxuebao.The clinical efficacy,incidence of thrombocytopenia,platelet count(PC)and platelet count changes were compared between the two groups.Results The total effective rate of treatment in the study group was higher than that in the control group(P<0.05).The incidence of thrombocytopenia in the study group was lower than that in the control group(P<0.05).The PC level of the two groups after treatment was higher than that before treatment,and the PC level of the study group was higher than that of the control group(P<0.05).The duration of platelet count<50×109/L,the time required to recover to 70×109/L,and the time required to recover to 100×109/L in the study group were shorter than those in the control group(P<0.05).Conclusion Interleukin-11 combined with Shengxuebao is effective in the treatment of thrombocytopenia after chemotherapy for malignant tumors.It can more effectively prevent thrombocytopenia after chemotherapy for malignant tumors,and shorten the time for platelet count to return to normal.

况福连;刘明盛

宜丰县人民医院内六科,江西 宜丰 336300宜丰县人民医院内六科,江西 宜丰 336300

临床医学

白细胞介素-11生血宝恶性肿瘤化疗血小板减少

Interleukin-11ShengxuebaoMalignant tumorChemotherapyThrombocytopenia

《医学信息》 2024 (24)

111-113,121,4

10.3969/j.issn.1006-1959.2024.24.030

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