摘要
Abstract
Objective To observe the efficacy and safety of different doses of remifentanil for painless gastroscopy.Methods A total of 63 patients who underwent painless gastroscopy in our hospital from March 2020 to March 2023 were selected as the research objects.They were divided into group A,group B and group C by random number table method,with 21 patients in each group.The control group was treated with 0.1 μg/kg remifentanil combined with propofol,the group B was treated with 0.3 μg/kg remifentanil combined with propofol,and the group C was treated with 0.6 μg/kg remifentanil combined with propofol.The anesthetic effect,anesthesia onset time,orientation recovery time,recovery time,vital signs[mean arterial pressure(MAP),heart rate(HR),oxygen saturation(SpO2)],the incidence of intolerance and the incidence of adverse reactions were compared among the three groups.Results The excellent and good rate of anesthesia in group B and group C was higher than that in group A(P＜0.05),but there was no significant difference between group B and group C(P＞0.05).The onset time of anesthesia,recovery time of directional force and recovery time in group C and group B were shorter than those in group A(P＜0.05),but there was no significant difference between group B and group C(P＞0.05).The MAP and HR of the three groups were lower than those before administration,and those of the group C were lower than those of group A and group B(P＜0.05),but there were no significant difference between group A and group B(P＞0.05).There was no significant difference in SpO2 between the three groups before and after administration(P＞0.05).The incidence of intolerance and adverse reactions in group C was higher than that in group A and group B(P＜0.05),but there was no significant difference between group A and group B(P＞0.05).Conclusion There are some differences in the efficacy and safety of different doses of remifentanil for painless gastroscopy,but relatively speaking,0.3 μg/kg remifentanil can not only achieve good anesthetic effect,but also reduce the incidence of adverse reactions and intolerance,maintain relatively stable vital signs,and maintain good quality of recovery after examination.关键词
不同剂量/瑞芬太尼/无痛胃镜检查/有效性/安全性Key words
Different doses/Remifentanil/Painless gastroscopy/Efficacy/Safety分类
医药卫生
