医学信息2024，Vol.37Issue(23)：109-112,4.DOI:10.3969/j.issn.1006-1959.2024.23.026
β2受体激动剂联合抗生素在慢性阻塞性肺病急性发作期的临床效果及安全性分析
Clinical Effect and Safety Analysis of β2 Receptor Agonist Combined with Antibiotics in Acute Exacerbation of Chronic Obstructive Pulmonary Disease
摘要
Abstract
Objective To observe the clinical effect and safety of β2 receptor agonist combined with antibiotics in acute exacerbation of chronic obstructive pulmonary disease.Methods During January,2022 and March,2023,80 patients with acute exacerbation of chronic obstructive pulmonary disease admitted to our hospital were collected,and grouped by random number table method,while 40 patients were enrolled in the routine group and 40 patients were enrolled in the research group.Antibiotics was used for treatment in the routine group,while the research group was added β2 receptor agonist on the basis of the method which was carry out in the routine group.Results In comparison with the routine group,the research group was observed to have a higher total effective rate(P＜0.05).Compared with the patients in the routine group after the treatment,6-minute walking distance,dyspnea grading scores,and FEV1,FEV1/FVC,PaO2,PaCO2 level in the research group were significantly superior to the routine group(P＜0.05).The incidence of adverse reactions in the research group was 7.50%,which was compared with 10.00%in the routine group,the difference was not statistically significant(P＞0.05).Conclusion β2 receptor agonist combined with antibiotics has a definite effect in the acute exacerbation of chronic obstructive pulmonary disease,which can reduce the dyspnea score of patients,improve the treatment efficiency,increase the 6-minute walking distance,improve lung function and blood gas index,and do not increase the incidence of clinical adverse reactions.It is worthy of clinical application.关键词
β2受体激动剂/抗生素/慢性阻塞性肺病/急性发作期/安全性Key words
β2 receptor agonist/Antibiotics/Chronic obstructive pulmonary disease/Acute exacerbation/Safety分类
医药卫生引用本文复制引用
甘建国,肖春雨,甘山花,江涛..β2受体激动剂联合抗生素在慢性阻塞性肺病急性发作期的临床效果及安全性分析[J].医学信息,2024,37(23):109-112,4.基金项目
2023年赣州市指导性科技计划项目(编号:2023DXNS4290) （编号:2023DXNS4290）
