中国防痨杂志2025，Vol.47Issue(1)：29-35,7.DOI:10.19982/j.issn.1000-6621.20240341
2014-2023年湖南省0～14岁儿童肺结核流行特征及变化趋势
The epidemiological characteristics and trends of tuberculosis among children aged 0-14 years in Hunan Province from 2014 to 2023
摘要
Abstract
Objective:To analyze the epidemiological characteristics and trends of tuberculosis among children aged 0-14 years in Hunan Province from 2014 to 2023,and to provide references for the formulation and adjustment of pediatric tuberculosis prevention and control policies.Methods:The surveillance data of tuberculosis among children aged 0-14 years in Hunan Province from 2014 to 2023 were collected from the Infectious Disease Surveillance System.The epidemiological characteristics of tuberculosis among children aged 0-14 years were analyzed during the study period,and the incidence trend was analyzed using Joinpoint regression model.Results:From 2014 to 2023,a total of 3350 cases of tuberculosis among children aged 0-14 were reported cumulatively in Hunan Province,with an average annual reported incidence rate of 2.64/100 000,and the reported incidence rate increased from 1.80/100 000(220 cases)in 2014 to 3.19/100 000(384 cases)in 2023,with an overall upward trend(x2trend=82.928,P＜0.001).The average annual incidence was 2.46/100 000(1691 cases)in boys and 2.85/100 000(1659 cases)in girls,and the reported incidence for girls was higher than those for boys,with a statistically significant difference(x2=17.870,P＜0.001).The reported incidence of tuberculosis among children aged 0-14 in Hunan Province from 2014 to 2023 showed an overall upward trend in Joinpoint regression analysis,with an average annual increase of 5.759％(AAPC=5.759％,95％CI:0.245％-11.577％,t=2.411,P=0.042).The variation tendency of girls was similar to that of all children,with an average annual increase of 7.511％(AAPC=7.511％,95％CI:0.471％-15.044％,t=2.466,P=0.039),and there was no statistically significant difference in the trend for boys(AAPC=4.066％,95％CI:-0.548％-8.893％,t=2.027,P=0.077).A total of 1030 cases with positive etiological test were reported,accounting for 30.75％(1030/3350)of all reported pediatric tuberculosis cases.The proportion of etiology positive tests increased from 21.82％in 2014(48/220)to 41.41％in 2023(159/384),showing a yearly increasing trend(x2trend=139.436,P＜0.001).The most cases were reported in October(12.21％,409/3350),and the cases reported throughout the year were mainly concentrated in July-October(44.99％,1507/3350).Conclusion:From 2014 to 2023,the reported incidence of tuberculosis among children aged 0-14 years in Hunan Province generally showed an upward trend,and the number of cases with etiology positive also increased year by year.The active surveillance efforts should be continued,and the prevention and control strategies should be adjusted in combination with the actual incidence of tuberculosis among children in various regions.关键词
结核/儿童/流行病学研究/模型,统计学Key words
Tuberculosis/Child/Epidemiologic studies/Models,statistical分类
临床医学引用本文复制引用
梁麟龙,裴异,周海依,谢齐放,张锋,江杰,刘富强..2014-2023年湖南省0～14岁儿童肺结核流行特征及变化趋势[J].中国防痨杂志,2025,47(1):29-35,7.基金项目
湖南省自然科学基金(2023JJ60405) （2023JJ60405）
长沙市指导性科技计划项目(kzd22073) （kzd22073）
长沙市中心医院科技计划重点项目(YNKY202303) Natural Science Foundation of Hunan Province(2023JJ60405) （YNKY202303）
Changsha Guiding Science and Technology Plan Project(kzd22073) （kzd22073）
Key Project of Changsha Central Hospital Technology Plan(YNKY202303) （YNKY202303）
