分析化学2024，Vol.52Issue(12)：1797-1806,10.DOI:10.19756/j.issn.0253-3820.241190
基于聚二甲基硅氧烷微流控芯片的微波生物传感器研究进展
Research Progress of Microwave Biosensors Based on Polydimethylsiloxane Microfluidic Chips
摘要
Abstract
Microwave biosensors are extensively applied in detection of food safety,environmental pollution and biomedical health.Compared to traditional optical and electrochemical sensing solutions,traditional optical and electrochemical sensor detection schemes,microwave sensing shows the advantages of high precision,strong penetration and non-contact detection.Polydimethylsiloxane(PDMS)exhibits numerous favorable characteristics in terms of integration,biocompatibility and processability.The integration of microwave biosensors with PDMS microfluidic chips allows for the full exploitation of the aforementioned advantages,thereby facilitating the provision of rapid,precise,and cost-effective detection solutions.These solutions are of considerable practical significance within the domain of biomedicine.This paper provides an overview of the fundamental characteristics and operational principles of microwave biosensors.It also offers a comprehensive account of the diverse types of microwave biosensors integrated with PDMS microfluidic chips,highlighting their respective advantages and disadvantages.Furthermore,it anticipates the challenges and potential solutions in the development of a novel generation of biosensor chip integration.This is with a view to providing a viable research and development concept for the advancement of medium and large-scale integrated-chip functional microfluidic chips in China.关键词
微流控技术/微波技术/生物传感器/聚二甲基硅氧烷/芯片一体化/评述Key words
Microfluidic technique/Microwave technique/Biosensor/Polydimethylsiloxane/Integrated chip/Review引用本文复制引用
王彦雄,陈仟龙,周小满,梁峻阁,姜岩峰,强天..基于聚二甲基硅氧烷微流控芯片的微波生物传感器研究进展[J].分析化学,2024,52(12):1797-1806,10.基金项目
国家自然科学基金项目(No.61801146)和中国博士后科学基金项目(No.2021M691284)资助. Supported by the National Natural Science Foundation of China(No.61801146)and the China Postdoctoral Science Foundation(No.2021M691284). （No.61801146）
