工业微生物2024，Vol.54Issue(6)：40-43,4.DOI:10.3969/j.issn.1001-6678.2024.06.014
双柏消肿止痛膏质量标准的研究
Study on the Quality Standards of the Shuangbai Xiaozhong Zhitong Cream
邱新华 1陈震尧 2夏静雯 2邓礼荷1
作者信息
- 1. 广东省肇庆医学院药学院,广东肇庆 526020
- 2. 广东省肇庆市中医院药剂科,广东肇庆 526020
- 折叠
摘要
Abstract
The article aims to establish a quality control method for Shuangbai Xiaozhong Zhitong Cream(a anti-inflammatory and pain relieving drug).Thin layer chromatography is used to identify the Angelica sinensis tail and red peony in the formula.High performance liquid chromatography is used to determine the content of berberine hydrochloride in phellodendron in the formula.Microscopic identification is used to identify rhubarb,phellodendron,platycladus orientalis leaves,and safflower in the formula.The thin-layer chromatography method for identifying Angelica sinensis tail and red peony has strong specificity and negative results without interference.The microscopic features such as cluster crystals of rhubarb,stone cells of phellodendron,stomata of platycladus orientalis leaves,and pollen grains of safflower are all obvious.The berberine hydrochloride in phellodendron exhibits a good linear relationship between 24.92-299.1 1ng(R2=1.000 0),with an average recovery rate of 102.3％(n=9)and an SRSD of 2.6％.The results show that this method is simple,highly specific,and reproducible,and can be used as a quality standard for Shuangbai Xiaozhong Zhitong cream.关键词
双柏消肿止痛膏/高效液相色谱/薄层色谱/显微鉴别/盐酸小檗碱/质量标准Key words
Shuangbai Xiaozhong Zhitong cream/high performance liquid chromatography/thin layer chromatography/microscopic identification/berberine hydrochloride/quality standard引用本文复制引用
邱新华,陈震尧,夏静雯,邓礼荷..双柏消肿止痛膏质量标准的研究[J].工业微生物,2024,54(6):40-43,4.
