工业微生物2024，Vol.54Issue(6)：64-68,5.DOI:10.3969/j.issn.1001-6678.2024.06.020
微生物发酵法生产L-丙氨酸的研究进展
Progress on Microbial Fermentation Production of L-alanine
聂玉朋 1任雪冰 1韩延雷 2田延军1
作者信息
- 1. 上海理工大学健康科学与工程学院,上海 200093
- 2. 齐鲁工业大学(山东省科学院),山东省食品发酵工业研究设计院,山东济南 250013
- 折叠
摘要
Abstract
L-alanine,one of the natural amino acids,is widely used in food,pharmaceutical and personal care applications.Currently,the production of L-alanine relies on economical,green and sustainable microbial fermentation using renewable carbon sources.In order to increase the fermentation titer of L-alanine,various metabolic engineering strategies have been employed to provide effective ways to reduce the production cost of L-alanine.This paper mainly reviews the metabolic engineering modification strategies and fermentation key technologies of high-titer L-alanine strains,with a view to providing references for the construction of subsequent high-titer L-alanine microbial cell factories.关键词
L-丙氨酸/微生物发酵/代谢工程Key words
L-alanine/microbial fermentation/metabolic engineering引用本文复制引用
聂玉朋,任雪冰,韩延雷,田延军..微生物发酵法生产L-丙氨酸的研究进展[J].工业微生物,2024,54(6):64-68,5.
