工业微生物2024，Vol.54Issue(6)：147-150,4.DOI:10.3969/j.issn.1001-6678.2024.06.040
穿心莲内酯纳米脂质载体的制备及表征
Preparation and Characterization of Andrographolide Nano-Lipid Carriers
陈艳萍 1黄冬怡 2黄婷婷 2廖伟菊 2邓润芳 2黄兴振2
作者信息
- 1. 广西医科大学药学院,广西南宁 536000||平乐县人民医院药剂科,广西桂林 542400
- 2. 广西医科大学药学院,广西南宁 536000
- 折叠
摘要
Abstract
The application value of andrographolide can be further developed by using the new preparation technique.In this study,andrographolide nano-lipid carriers were synthesized by using the melt-emulsification-ultrasonication-low temperature solidification method with process parameters improved.The ideal circumstances were a compound of glyceryl monostearate and isopropyl myristate,Tween-80 as a surfactant,a solid-to-liquid lipid ratio of 1∶1,The drug-lipid ratio was 1∶20 and emulsified for 60 min in a 75℃ water bath.This study can provide a theoretical basis for further development of andrographolide.关键词
穿心莲内酯/纳米脂质载体/表征/工艺优化Key words
AG/AG-NLCs/optimization of liposomal carriers引用本文复制引用
陈艳萍,黄冬怡,黄婷婷,廖伟菊,邓润芳,黄兴振..穿心莲内酯纳米脂质载体的制备及表征[J].工业微生物,2024,54(6):147-150,4.
