化工进展2024，Vol.43Issue(12)：6913-6924,12.DOI:10.16085/j.issn.1000-6613.2023-2049
蓖麻油基水性聚氨酯载药乳液的制备及性能
Preparation and properties of castor oil-based waterborne polyurethane drug-loaded emulsion
摘要
Abstract
To reduce the environmental pollution caused by pesticides and improve the effective application of the hydrophobic pesticide avermectin(AVM)in crops,castor oil-based waterborne polyurethane emulsion(CP)synthesized by self-emulsification method was coated AVM to obtain the drug-loaded emulsion(CPA).The chemical structure,microstructure,thermal stability,contact angle,leaf retention,ultraviolet resistance,sustained release performance,insecticidal activity and storage stability of drug-loaded emulsions with different castor oil(CO)contents were studied.The results showed that compared with AVM dispersion,the contact angle of CPA on cucumber leaves decreased by more than 20%and the retention increased by more than 50%,which indicated that CPA had better affinity and wettability on cucumber leaves.Under the same UV irradiation,the half-life of CPA was nearly half longer than AVM dispersion,indicating that CPA had good ultraviolet resistance.The drug loading rate of CPA was between 5.61%and 6.62%and the encapsulation efficiency was more than 70%.It had good sustained release performance.The drug release behavior conformed to the First-order kinetic model and was controlled by Fickian diffusion.There was no significant difference between CPA and AVM dispersion in the insecticidal activity against plutella xylostella.关键词
蓖麻油/水性聚氨酯/缓释/乳液/载体/稳定性Key words
castor oil/waterborne polyurethane/sustained release/emulsions/support/stability分类
化学化工引用本文复制引用
黄雪,范燕香,周红军,周新华,窦瑶..蓖麻油基水性聚氨酯载药乳液的制备及性能[J].化工进展,2024,43(12):6913-6924,12.基金项目
广东省普通高校重点领域专项(2023ZDZX4022,2021ZDZX2056) （2023ZDZX4022,2021ZDZX2056）
成都职业技术学院科研团队项目(20KYTD07) （20KYTD07）
广东省重点领域研发计划(2023B0202080002). （2023B0202080002）
