首页|期刊导航|临床眼科杂志|低剂量睫状体光凝术治疗急性闭角型青光眼持续高眼压状态的安全性分析

低剂量睫状体光凝术治疗急性闭角型青光眼持续高眼压状态的安全性分析OACSTPCD

Safety of low-does transscleral diode laser cyclophotocoagulation for the treatment of acute primary angle-closure glaucoma under persistent high intraocular pressure

中文摘要英文摘要

目的 分析原发性急性闭角型青光眼(APACG)持续高眼压状态下应用低剂量睫状体光凝术治疗的安全性.方法 回顾性分析2020年1月至2023年2月在我院治疗的持续高眼压APACG合并白内障患者73例(73只眼),按照手术处理方式不同分为两组,试验组35例(35只眼)先行低剂量睫状体光凝术后再行白内障超声乳化吸除联合房角分离手术间隔(2.49±0.26)周,对照组38例(38只眼)在高眼压状态下直接行白内障超声乳化吸除联合房角分离手术.比较两组经非手术治疗后的眼压,超声乳化术前的眼压,超声乳化术后1 d、1周、1个月及3个月眼压,以及超声乳化术中后囊破裂、虹膜脱垂发生率和术后一过性高眼压、瞳孔区炎性渗出、角膜水肿发生率.结果两组经非手术治疗后的眼压和超声乳化术后1周、1个月、3个月的眼压差异均无统计学意义(均P>0.05),试验组超声乳化术前、术后1 d的眼压低于对照组(均P<0.05).试验组超声乳化术中虹膜脱垂发生率以及术后一过性高眼压、瞳孔区炎性渗出、角膜水肿发生率均低于对照组(均P<0.05).两组术中后囊破裂发生率差异无统计学意义(P>0.05).结论 APACG持续高眼压状态可先采用低剂量睫状体光凝术,待眼压下降及前房炎症控制后再行白内障超声乳化吸除联合房角分离手术,可有效控制眼压并明显降低术中及术后并发症的发生率.

Objective To analyze the safety of low-dose transscleral diode laser cyclophotocoagulation(TDCP)for the treatment of acute primary angle-closure glaucoma(APACG)under persistent high intraocular pressure(IOP).Methods A retrospective case series study.73 APACG with cataract patients(73 eyes)under persistent high IOP from January 2020 to February 2023 were retrospectively analyzed.The experimental group(35 eyes)was treated with low-dose TDCP followed by phacoemulsification combined with goniosynechialysis(2.49±0.26 w intervals).The control group(38 eyes)was treated with phacoemulsification combined with goniosynechialysis alone.IOP was compared between the two groups after nonoperative treatment,before phacoemulsification and 1day,1week,1month,3months after phacoemulsifica-tion.The incidence of intraoperative and postoperative complications was also compared between the two groups.Results There were no statistical differences in IOP between the two groups after nonoperative treatment and 1 week,1 month,3 months after phacoemulsification(all P>0.05).However,the IOP of the experimental group was lower than that of the control group before phacoemulsification and 1 day after phacoemulsification,there was a significant difference between the two groups(all P<0.05).The incidence of iris prolapse and transient high IOP,exudation in the pupil area,corneal edema after phacoemulsification in the experimental group was significantly lower than that in the control group(all P<0.05).But there was no statistical difference in the incidence of posterior capsular rupture between the two groups.Conclu-sions APACG under persistent high IOP can be treated with low-dose TDCP followed by phacoemulsification combined with goniosynechialysis after IOP reduction and intraocular inflammation was controlled.It can effectively control IOP and significantly reduce the incidence of intraoperative and postoperative complications.

赖钟祺;李维娜

362000 泉州,中国人民解放军联勤保障部队第910医院眼科362000 泉州,中国人民解放军联勤保障部队第910医院眼科

睫状体光凝急性闭角型青光眼超声乳化

CyclophotocoagulationAcute primary angle-closure glaucomaPhacoemulsification

《临床眼科杂志》 2024 (6)

522-525,4

10.3969/j.issn.1006-8422.2024.06.009

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