西南医科大学学报2025，Vol.48Issue(1)：27-31,5.DOI:10.3969/j.issn.2096-3351.2025.01.006
慢性乙型肝炎临床治愈的研究现状与前景
Current Status and Prospects of Clinical Cure for Chronic Hepatitis B
摘要
Abstract
Chronic hepatitis B is a progressive disease that leads to a significant number of deaths each year due to cirrhosis and hepatocellular carcinoma.In recent years,with the deepening understanding of the mechanisms of Hepatitis B virus infection,advance-ments in different transformation strategies for nucleos(t)ide analogs and long-acting interferons,and the development of new drugs,a cure for hepatitis B has become an achievable goal.This paper reviewed the concept of clinical cure for hepatitis B,its historical devel-opment,potential mechanisms,the current treatment landscape,and the latest progress in new drug development.The challenges encountered in the process of curing hepatitis B and directions for future efforts were also discussed,providing a reference for clinical research and practice.关键词
慢性乙型肝炎/临床治愈/治疗策略/核苷(酸)类似物/干扰素Key words
Chronic hepatitis B/Clinical cure/Treatment strategies/Nucleos(t)ide analogs/Interferon分类
临床医学引用本文复制引用
彭语晨,邬小萍..慢性乙型肝炎临床治愈的研究现状与前景[J].西南医科大学学报,2025,48(1):27-31,5.基金项目
江西省自然科学基金(20212ACB206010) （20212ACB206010）
