西南医科大学学报2025，Vol.48Issue(1)：105-110,6.DOI:10.3969/j.issn.2096-3351.2025.01.020
Fe3O4磁性纳米材料在医学领域中的研究进展
Research Progress of Fe3O4 Mgnetic Nanomaterials in the Medical Field
摘要
Abstract
With the progression of nanotechnology,magnetic nanomaterials,especially magnetite(Fe3O4)nanoparticles,have increasingly showcased their pivotal role in the field of medicine.The Fe3O4 magnetic nanomaterials garner considerable interest from researchers due to their unique magnetic properties,superior biocompatibility,and facile surface functionalization capabilities.Under the influence of external magnetic fields,these materials demonstrate rapid and directed mobility.Furthermore,their nanoscale dimen-sions give rise to high specific surface areas and enhanced surface energies,which facilitate the efficient adsorption and conjugation of drug molecules and biomolecules.Moreover,the stable chemical properties and low biotoxicity of Fe3O4 magnetic nanomaterials render them highly promising for various medical applications.In biomedical research,Fe3O4 magnetic nanomaterials have been widely adopted across multiple domains and achieved notable advancements.This article presented a comprehensive overview of the research advances of Fe3O4 magnetic nanomaterials in diverse areas such as drug delivery systems,tumor hyperthermia therapy,blood purifica-tion,enzyme-catalyzed therapy,magnetic resonance imaging(MRI),protein and nucleic acid separation and purification,and cell separation and immune analysis.It also looked forward to potential development paths and innovation points in the technology..关键词
Fe3O4磁性纳米材料/药物载体/肿瘤热疗/血液净化/酶催化治疗/核磁共振成像/蛋白质与核酸的分离提纯/细胞分离/免疫分析Key words
Fe3O4 magnetic nanomaterials/Drug delivery systems/Tumor hyperthermia therapy/Blood purification/Enzyme-catalyzed therapy/Magnetic resonance imaging(MRI)/Protein and nucleic acid separation and purification/Cell separation/Immune analysis分类
医药卫生引用本文复制引用
严肖,徐姚,张静,袁茜,柯发敏..Fe3O4磁性纳米材料在医学领域中的研究进展[J].西南医科大学学报,2025,48(1):105-110,6.基金项目
教育部"春晖计划"合作科研项目(202200618) （202200618）
大学生创新创业训练计划项目(202310632087) （202310632087）
