钙磷基生物陶瓷材料的计算模拟进展与挑战OA
The Progress and Challenges in Computational Simulation of Calciumphosphorus-based Bioceramics
钙磷基生物陶瓷材料在生物医学领域,特别是骨修复和替代方面,展现出广阔的应用前景.传统的实验方法受制于漫长的时间、高昂的成本以及极端的条件而引入的计算模拟技术,在理解和优化材料的性能方面发挥了至关重要的作用.结合国内外研究和本小组近年的相关工作,总结钙磷基生物陶瓷材料的计算模拟进展和面临的诸多挑战,展望该领域的未来发展,强调通过结合先进的计算方法与实验验证,有望进一步推动钙磷基生物陶瓷材料在生物医学中的应用和发展.
Calciumphosphorus-based(CaP)bioceramic materials demonstrate significant potential in the biomedical field,particu-larly for bone repair and replacement.Traditional experimental methods are often constrained by long durations,high costs,and strin-gent conditions.The introduction of computational simulation technology plays a crucial role in understanding and optimizing the per-formance of CaP bioceramic materials.The progress in the computational simulation of CaP bioceramic materials is reviewed in this pa-per,drawing on both domestic and international research as well as recent work from our group.The numerous challenges currently faced in this area are highlighted.Finally,the future development of this field is anticipated,and the importance of advanced computa-tional methods combined with experimental verification is emphasized.This is expected to further promote the application and develop-ment of CaP bioceramic materials in biomedicine.
张巧;徐定国
四川大学化学学院,四川成都 610064四川大学化学学院,四川成都 610064
化学
生物陶瓷材料计算模拟骨组织工程羟基磷灰石
bioceramic materialscomputational simulationbone tissue engineeringhydroxyapatite
《四川师范大学学报(自然科学版)》 2025 (2)
166-175,10
国家自然科学基金(21973064)
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