湖北科技学院学报（医学版）2025，Vol.39Issue(1)：48-52,5.DOI:10.16751/j.cnki.2095-4646.2024072407
危重症中心静脉穿刺置管患者深静脉血栓形成的影响因素分析
Analysis of Influencing Factors for Deep Vein Thrombosis Formation in Patients with Central Venous Catheterization in the Intensive Care Unit
高坡 1吕智全 1屈世全 1李泉 2张为明 1周伟伟 1刘静 1黄晨钊 2李云3
作者信息
- 1. 安徽医科大学附属阜阳医院急诊重症监护室,安徽 阜阳 236000
- 2. 安徽医科大学附属阜阳医院急诊内科
- 3. 安徽医科大学附属阜阳医院消化内科
- 折叠
摘要
Abstract
Objective To explore the incidence of deep vein thrombosis(DVT)and its influencing factors in critically ill patients with central venous catheterization.Methods A retrospective analysis was performed,encompassing 115 patients who un-derwent central venous catheterization procedures in our hospital's Emergency Intensive Care Unit(EICU).Patients were catego-rized into a thrombosis group and a non-thrombosis group based on the occurrence of DVT after catheterization.A comparative anal-ysis of clinical profiles was conducted,and factors with significant statistical disparities were subjected to multivariate analysis to i-dentify determinants influencing DVT development.The sensitivity and specificity of these factors in predicting DVT were assessed using the receiver operating characteristic(ROC)curve.Results Among 115 patients 24 developed DVT,and the top three types of thrombosis in DVT were simple intermuscular vein thrombosis,multiple deep vein thromboses in the lower limbs,and mural throm-bi.The top three diseases associated with DVT were acute respiratory infections,malignancies,and acute digestive hemorrhagic dis-eases.Significant statistical differences were observed between the two groups in terms of infection,malignancy,hyperlipidemia,history of thrombosis,duration of catheter retention,platelet count(PLT),prothrombin time(PT),and D-dimer levels(all P＜0.05).Multivariate analysis revealed that hyperlipidemia,thrombosis history,catheter retention duration,and D-dimer levels were independent risk factors for DVT in catheterized patients.ROC curve analysis indicated that both catheter retention duration and D-dimer levels are significant predictors of DVT,with the former showing the highest area under the curve(AUC=0.765)and an op-timal cutoffpoint of 2.5 days,offering the sensitivity and specificity of 85.7%and 57.1%,respectively,for DVT prediction.Con-clusion The incidence of DVT in critically ill patients with central venous catheterization is high,and it should be taken seriously in clinical practice.Hyperlipidemia,thrombosis history,catheter retention duration,and D-dimer levels are independent risk factors for DVT,among which the duration of catheter retention has the greatest value in predicting the formation of DVT.关键词
重症监护病房/中心静脉导管/静脉血栓形成/急诊室/Logistic回归分析模型Key words
Intensive care units/Central venous catheters/Venous thrombosis/Emergency service/Logistic models分类
医药卫生引用本文复制引用
高坡,吕智全,屈世全,李泉,张为明,周伟伟,刘静,黄晨钊,李云..危重症中心静脉穿刺置管患者深静脉血栓形成的影响因素分析[J].湖北科技学院学报（医学版）,2025,39(1):48-52,5.
