湖北科技学院学报（医学版）2025，Vol.39Issue(1)：84-88,5.DOI:10.16751/j.cnki.2095-4646.2024062409
海马在疼痛抑郁共病中的研究进展
Research Progress of Hippocampus in Pain and Depression Comorbidity
摘要
Abstract
The hippocampus is an important region of the brain that plays a role in memory,emotions and stress respon-ses.Pain and depression often co-occur clinically,and pain often worsens depressive symptoms,and vice versa.Structural and functional changes in the hippocampus are considered to be important neurobiological mechanisms of pain and depression comor-bidity.This paper reviews the relationship between morphological and neurochemical changes in the hippocampus with depression,chronic pain and pain depression comorbidities.These studies provide a new perspective for understanding the pathophysiological mechanisms of pain and depression comorbidity,and provide the possibility for developing new treatment strategies.关键词
疼痛抑郁共病/海马神经可塑性变化/慢性疼痛/抑郁Key words
Pain and depression comorbidity/Neuroplasticity of hippocampus/Chronic pain/Depressed分类
医药卫生引用本文复制引用
刘佳睿,李岱,朱海丽..海马在疼痛抑郁共病中的研究进展[J].湖北科技学院学报（医学版）,2025,39(1):84-88,5.基金项目
国家自然科学基金资助项目(81971066) （81971066）
