中风与神经疾病杂志2024，Vol.41Issue(12)：1148-1152,5.DOI:10.19845/j.cnki.zfysjjbzz.2024.0220
外周免疫在阿尔茨海默病发生发展中作用的研究进展
Research advances on the role of peripheral immunity in the development and progression of Alzheimer disease
摘要
Abstract
Alzheimer disease(AD),a degenerative disease of the central nervous system characterized by progres-sive cognitive dysfunction and behavioral impairment,has gradually become one of the most burdensome diseases in this century.At present,the amyloid cascade hypothesis is a widely recognized theory on the pathogenesis of AD.However,recent studies have shown that the immune system can play an important role in the occurrence of AD.This article summa-rizes the relationship between the immune system and the development and progression of AD from the existing literature,with an emphasis on the role of peripheral immunity in both the innate and adaptive immune systems,aiming to provide novel ideas for future research on AD in the immunological direction.关键词
阿尔茨海默病/外周免疫/发病机制Key words
Alzheimer disease/Peripheral immunity/Pathogenesis分类
医药卫生引用本文复制引用
崔灿,何谦益,丁志方,岳悦,赵莘瑜..外周免疫在阿尔茨海默病发生发展中作用的研究进展[J].中风与神经疾病杂志,2024,41(12):1148-1152,5.基金项目
河南省医学科技攻关计划联合共建项目(LHGJ20210301) （LHGJ20210301）
