摘要
Abstract
Objective:To summarize the clinical and CT characteristics of abdominal Burkitt's lymphoma (BL) in children,analyze the causes of misdiagnosis,and improve the diagnostic accuracy of abdominal BL in children. Methods:A retrospec-tive analysis focused on 42 children with pre-therapy CT data and 71 with clinical data of abdominal BL. The clinical char-acteristics of 71 cases of abdominal BL in children were studied,as well as the CT characteristics of 42 cases and as well as the causes of misdiagnosis. Results:Of the 71 children with abdominal BL,60 were males and 11 were females,with an av-erage age of 6.8±0.1 years. Among them,24 cases were in the early stage(Ⅰ+Ⅱ,33.8%) and 47 cases were in the late stage (Ⅲ+Ⅳ,66.2%). Sixty-three cases(88.7%) showed overall remission,and 8 cases(12.3%) died. Before therapy,42 cases under-went plain and enhanced abdomen CT scans. A total of 31 cases(73.8%) had gastrointestinal tract involvement,while 20 cases (47.6%) had peripheral organ invasion. The accuracy rate of CT diagnosis before treatment was 81%. Children 's abdominal BL was divided into three types according to the cause of the CT misdiagnosis:gastrointestinal type,nodular type,and hybrid type. Fourteen cases of gastrointestinal type(33.3%) displayed diffuse thickening of the intestinal(gastric) wall. Fifteen cases of nodule type (35.7%) displayed soft tissue masses with no significant intestinal wall thickening. Thirteen cases of hybrid type (31.0%) displayed diffuse thickening of the intestinal wall and lymph node enlargement,and urinary system infiltration was more common than gastrointestinal and nodule type (P=0.024). Conclusion:Abdominal BL in children often involves the gas-trointestinal tract and is characterized by diffuse thickening of the intestinal (gastric) wall and soft tissue masses,which are prone to peripheral tissue infiltration. The gastrointestinal type is easily misdiagnosed as a stromal tumor,the nodular type is easily misdiagnosed as a malignant tumor,and the hybrid type has typical imaging manifestations,most of which can be ac-curately diagnosed.关键词
伯基特淋巴瘤/腹部肿瘤/儿童/误诊/体层摄影术,X线计算机Key words
Burkitt Lymphoma/Abdominal Neoplasms/Child/Diagnostic Errors/Tomography,X-ray Computed分类
医药卫生