儿科药学杂志2025，Vol.31Issue(1)：36-40,5.DOI:10.13407/j.cnki.jpp.1672-108X.2025.01.007
我院双嘧达莫在儿童患者的临床应用分析
Clinical Application of Dipyridamole in Children in Our Hospital
刘翌 1唐盈 1陈章华 1刘明 1莫小兰 1张玉霞1
作者信息
- 1. 广州市妇女儿童医疗中心,广州 510623
- 折叠
摘要
Abstract
Objective:To analyze the clinical application of dipyridamole in children,so as to provide reference for rational application and off-label use of dipyridamole in children.Methods:Medical records of patients under 18 years with dipyridamole from Feb.22nd,2016 to May 29th,2022 in Guangzhou Women and Children's Medical Center were extracted.The basic information,disease diagnosis and duration of medication dosage were analyzed.Results:A total of 2,381 medical records were extracted,including 1,567 males and 814 females.There were 250 children aged from 0 to 1 year,446 children aged from 1 to 3 years,and 1,483 children aged from＞3 to 12 years.The main diagnosis were renal diseases,gastrointestinal diseases,respiratory diseases,cardiovascular diseases and hematological diseases.Patients were mostly administered within 30 d,with continuous daily doses ranging from 12.5 to 250.0 mg and temporary daily doses ranging from 3.0 to 250.0 mg.Daily doses were positively correlated with patients'age,yet the correlation was weak.The off-label indication of dipyridamole at the hospital was partially supported by guidelines,literature or clinical trial evidence.The off-label age was supported by evidence,and was consistent with the recommended dosage.Conclusion:No adverse drug reactions have been documented for the clinical application of dipyridamole for specific diseases in pediatrics.关键词
双嘧达莫/儿童用药/临床数据分析Key words
dipyridamole/pediatric drug use/clinical data analysis分类
医药卫生引用本文复制引用
刘翌,唐盈,陈章华,刘明,莫小兰,张玉霞..我院双嘧达莫在儿童患者的临床应用分析[J].儿科药学杂志,2025,31(1):36-40,5.
