影像科学与光化学2025，Vol.43Issue(1)：41-47,7.DOI:10.7517/issn.1674-0475.2025.01.07
高频超声与脂肪肝指数联合评估在健康体检中诊断脂肪肝的价值
The Diagnostic Efficacy of High-frequency Ultrasound Combined with Fatty Liver Index(FLI)for Metabolic Dysfunction-associated Fatty Liver Disease(MAFLD)in Health Examinations
摘要
Abstract
Objective:To explore the diagnostic efficacy of combining liver-spleen index measured by high-frequency ultrasound with fatty liver index(FLI)for metabolic dysfunction-associated fatty liver disease(MAFLD)in health examinations.Methods:A total of 80 MAFLD patients undergoing health examinations at the Comprehensive Diagnostic and Treatment Health Examination Department Ⅱ of the First Affiliated Hospital of Air Force Medical University from January 2022 to March 2024 were selected as the MAFLD group.Another 80 individuals undergoing health examinations during the same period were selected as the control group.Clinical data of the subjects were collected,liver-spleen index was measured using high-frequency ultrasound,and FLI was calculated.Logistic regression analysis was used to analyze factors influencing MAFLD diagnosis.Receiver operating characteristic(ROC)curve analysis was performed to evaluate the diagnostic efficacy of liver-spleen index measured by high-frequency ultrasound and FLI for MAFLD.Results:Compared with the control group,the MAFLD group showed statistically significant differences in aspartate aminotransferase(AST),triglycerides(TG),low-density lipoprotein cholesterol(LDL-C),liver-spleen index measured by high-frequency ultrasound,and FLI(P＜0.05).Logistic regression analysis showed that liver-spleen index measured by high-frequency ultrasound(OR=1.415,95％CI=1.224-1.635,P＜0.05)and FLI(OR=1.060,95％CI=1.009-1.114,P＜0.05)were influencing factors for MAFLD diagnosis.ROC curve analysis showed good diagnostic efficacy for MAFLD with liver-spleen index measured by high-frequency ultrasound(area under the curve(AUC)=0.870)and FLI(AUC=0.893),while the combined detection achieved an AUC of 0.950.Conclusion:The combination of liver-spleen index measured by high-frequency ultrasound and FLI can significantly improve the diagnostic efficacy for MAFLD,providing a powerful tool for early screening in health examinations.关键词
代谢相关脂肪性肝病/高频超声/肝脾指数/脂肪肝指数/健康体检Key words
metabolic dysfunction-associated fatty liver disease/high-frequency ultrasound/liver-spleen index/fatty liver index/health examination分类
医药卫生引用本文复制引用
耿烨,李艳艳..高频超声与脂肪肝指数联合评估在健康体检中诊断脂肪肝的价值[J].影像科学与光化学,2025,43(1):41-47,7.基金项目
陕西省科技统筹创新工程计划项目(2016TZC-S-15-12). （2016TZC-S-15-12）
