高压物理学报2025，Vol.39Issue(2)：1-7,7.DOI:10.11858/gywlxb.20240831
适用于同步辐射小角X射线散射的高压溶液装置及其应用
Applications of High-Pressure Solution Device for Synchrotron Radiation Small Angle X-Ray Scattering Method
摘要
Abstract
High pressure is one of the fundamental thermodynamic parameters,which can induce the structural changes in soft matter systems.By combining the spatial resolution of small-angle X-ray scattering(SAXS),this technique can be employed to explore the dynamics of protein folding and the mechanisms of nucleic acid structural stability.Moreover,it has promising and broad applications in the field of life sciences.Currently,the specialized equipment for high-pressure solution scattering is still lacking in China.For this purpose,a high-pressure in-situ sample device and a manual pressurization system for specialized solution X-ray scattering have been developed at BL19U2 beamline at SSRF,which can complete the hydrostatic pressure measurements from 0.1 to 250 MPa.More important,the apparatus can keep the X-ray window in the same place throughout the experiment,which can help to subtract the accurate background scattering and achieve the measurements with high signal-to-noise ratio.This will provide a valuable research platform for wide range of areas,including food science,pharmacology,and structural biology.关键词
上海同步辐射装置/高压溶液散射装置/小角X射线散射/软物质Key words
Shanghai synchrotron radiation facility/high pressure solution scattering apparatus/small angle X-ray scattering/soft matter分类
数理科学引用本文复制引用
刘广峰,李怡雯,张建桥,宋攀奇,李娜..适用于同步辐射小角X射线散射的高压溶液装置及其应用[J].高压物理学报,2025,39(2):1-7,7.基金项目
国家自然科学基金(12105350) （12105350）
中国科学院青年创新促进会项目(2020289) （2020289）
