实用临床医药杂志2024，Vol.28Issue(23)：1-7,7.DOI:10.7619/jcmp.20243021
基于CiteSpace软件的癌症领域孟德尔随机化研究的知识图谱可视化分析
Visual analysis of the knowledge map of Mendelian randomization studies in the field of cancer based on CiteSpace software
摘要
Abstract
Objective To conduct a visual analysis of the literature related to Mendelian random-ization(MR)studies in the field of cancer based on CiteSpace software.Methods English literature on MR studies in the field of cancer was searched in the Web of Science Core Collection database,and Chinese literature was searched in CNKI,Wanfang Data,and VIP databases.The search period ranged from the inception of the databases to April 18,2024.CiteSpace 6.3.R1 software was used to perform a visual analysis of the publication trends,authors,institutions,and keywords of the included literature through knowledge mapping.Results A total of 964 English articles and 121 Chinese arti-cles were included in this study.The annual publication of English and Chinese literature on MR stud-ies in the field of cancer showed an overall upward trend,but there was limited collaboration among authors and institutions.The analysis of keywords in both English and Chinese literature revealed that breast cancer,colorectal cancer,lung cancer,prostate cancer,and gastric cancer were the key cancer types,with sex hormones and low back pain as the main associated factors.Research hotspots lasting for more than five years included genetic polymorphism,colorectal cancer,and genome-wide association studies.The recent research hotspots focused on insulin,renal cell carcinoma,and endometrial cancer.Conclusion MR studies have been extensively conducted in the field of cancer and have become a research hotspot.However,collaboration among authors and institutions still need to be strengthened.The inherent limitations of the research methodology itself can lead to issues such as insufficiency of MR study evidence and conflicting results among different studies.Future MR stud-ies should integrate other disciplines and epidemiological research methods to provide more compre-hensive causal evidence.关键词
癌症/孟德尔随机化/CiteSpace/知识图谱/文献计量学分析/可视化分析Key words
cancer/Mendelian randomization/CiteSpace/knowledge map/bibliometric a-nalysis/visual analysis分类
医药卫生引用本文复制引用
张恺悦,魏莱,黄源鹏..基于CiteSpace软件的癌症领域孟德尔随机化研究的知识图谱可视化分析[J].实用临床医药杂志,2024,28(23):1-7,7.基金项目
国家自然科学基金项目(82074508) （82074508）
福建省自然科学基金项目(青创项目)(2023J05282) （青创项目）
福建省自然科学基金项目(面上项目)(2023J011627) （面上项目）
福建省厦门市扶持中医药发展专项重点项目(XWZY-2023-0603) （XWZY-2023-0603）
福建省名老中医药专家传承工作室项目[闽卫中医函(2023)697号] （2023）
