内科理论与实践2024,Vol.19Issue(5):322-327,6.DOI:10.16138/j.1673-6087.2024.05.07
慢性阻塞性肺疾病合并阻塞性睡眠呼吸暂停的生物标志物研究进展
Research progress on biomarkers for chronic obstructive pulmonary disease complicated with obstructive sleep apnea
摘要
Abstract
The coexistence of obstructive sleep apnea(OSA)and chronic obstructive pulmonary disease(COPD)is referred to as COPD-OSA overlap,also known as overlap syndrome(OS).OS patients are more severe and have worse prognosis than those with OSA and COPD alone.Because pulmonary function and polysomnography cannot be conducted widely for patients,at present,there are many research to explore the clinical value of immunology,blood cell,gene protein,body fluid and other related biomarkers related to OS in assisting diagnosis,predicting the risk and severity of disease.This article reviews the recent research progress on OS-related biological markers.关键词
重叠综合征/生物标志物/慢性阻塞性肺疾病/阻塞性睡眠呼吸暂停Key words
Overlapping syndrome/Biomarkers/Chronic obstructive pulmonary disease/Obstructive sleep apnea分类
医药卫生引用本文复制引用
强士豪,戴晴霞,黄丽娜,郭华,崔小川..慢性阻塞性肺疾病合并阻塞性睡眠呼吸暂停的生物标志物研究进展[J].内科理论与实践,2024,19(5):322-327,6.基金项目
国家自然科学基金项目(82200106) (82200106)