辽宁大学学报(自然科学版)2024,Vol.51Issue(4):327-331,5.
特泊替尼(Tepotinib)合成路线图解
Graphical Synthesis Routes of Tepotinib
摘要
Abstract
Tepotinib is an oral c-Met inhibitor developed by Merck KGaA Pharmaceuticals.Tepotinib is the first small molecule inhibitor for the treatment of Met mutant non-small cell lung cancer.This article summarizes the synthesis process of Tepotinib to provide new ideas for the design of the synthesis routes of Tepotinib.关键词
特泊替尼/c-Met/合成路线Key words
Tepotinib/c-Met/synthesis routes分类
医药卫生引用本文复制引用
刘举,金凡琪,林艺涵,杨敏,李春艳,丁实,周云鹏..特泊替尼(Tepotinib)合成路线图解[J].辽宁大学学报(自然科学版),2024,51(4):327-331,5.基金项目
沈阳市自然科学基金(23-503-6-12) (23-503-6-12)
辽宁省自然科学基金计划面上项目(2022-MS-169) (2022-MS-169)