上海针灸杂志2025，Vol.44Issue(1)：93-98,6.DOI:10.13460/j.issn.1005-0957.2025.01.0093
腕踝针联合桃红四物汤治疗血脉瘀阻型Ⅰ～Ⅱ期下肢动脉硬化闭塞症疗效观察
Observations on the efficacy of wrist-ankle acupuncture plus Tao Hong Si Wu decoction for stage Ⅰ and Ⅱ lower extremity arteriosclerosis obliterans of blood stasis type
摘要
Abstract
Objective To observe the clinical efficacy of wrist-ankle acupuncture plus Tao Hong Si Wu decoction for stage Ⅰ and Ⅱ lower extremity arteriosclerosis obliterans of blood stasis type.Methods Ninety-eight patients with stage Ⅰ and Ⅱ lower extremity arteriosclerosis obliterans of blood stasis type were randomized to observation and control groups,with 49 cases in each group.The control group was treated with Tao Hong Si Wu decoction and the observation group,with wrist-ankle acupuncture in addition.The TCM symptom score,ultrasound indicators(dorsal pedal artery peak flow velocity,inner diameter and blood flow volume),the ankle-brachial index,the arteriosclerosis index,vascular endothelial function(serum nitric oxide and endothelin-1 levels)and hemorheological indicators(low-shear whole blood viscosity,high-shear whole blood viscosity and plasma viscosity)were observed in the two groups before and after treatment.The clinical therapeutic effects and adverse reactions were compared between the two groups.Results The total efficacy rate was 91.5% in the observation group,which was significantly higher than 76.6% in the control group(P＜0.05).After treatment,the limb numbness score,the limb chill score and the limb pain score decreased in the two groups compared with before(P＜0.05)and were lower in the observation group than in the control group(P＜0.05).After treatment,the vascular peak flow velocity,inner diameter and blood flow volume increased in the two groups compared with before(P＜0.05)and were higher in the observation group than in the control group(P＜0.05).After treatment,the ankle-brachial index increased and the arteriosclerosis index decreased in the two groups compared with before(both P＜0.05)and they were better in the observation group than in the control group(P＜0.05).After treatment,serum nitric oxide levels increased and endothelin-1 levels decreased in the two groups compared with before(both P＜0.05)and they were better in the observation group than in the control group(P＜0.05).After treatment,low-shear whole blood viscosity,high-shear whole blood viscosity and plasma viscosity decreased in the two groups compared with before(P＜0.05)and were lower in the observation group than in the control group(P＜0.05).No serious adverse reactions occurred in the two groups during treatment.Conclusion Wrist-ankle acupuncture plus Tao Hong Si Wu decoction has a marked clinical effect on stage Ⅰ and Ⅱ lower extremity arteriosclerosis obliterans of blood stasis type.关键词
针刺疗法/腕踝针/针药并用/桃红四物汤/血脉瘀阻/下肢动脉硬化闭塞症/血管内皮/血液流变学Key words
Acupuncture therapy/Wrist-ankle acupuncture/Acupuncture medication combined/Tao Hong Si Wu decoction/Blood stasis/Lower extremity arteriosclerosis obliterans/Vascular endothelium/Hemorheology分类
医药卫生引用本文复制引用
李晨阳,赵钢,李欣然,陈文阁..腕踝针联合桃红四物汤治疗血脉瘀阻型Ⅰ～Ⅱ期下肢动脉硬化闭塞症疗效观察[J].上海针灸杂志,2025,44(1):93-98,6.基金项目
黑龙江省卫生健康委科研课题(20210404130252) （20210404130252）
