日用化学工业（中英文）2025，Vol.55Issue(1)：89-97,9.DOI:10.3969/j.issn.2097-2806.2025.01.011
表皮葡萄球菌应用于化妆品的研究进展
Research progress of Staphylococcus epidermidis applied in cosmetics
文霞 1冯静 1刘静霞 1徐健 2陈相孩 3谢小保1
作者信息
- 1. 广东省科学院微生物研究所 广东省微生物分析检测中心 华南应用微生物国家重点实验室广东省菌种保藏与应用重点实验室,广东 广州 510070
- 2. 广东迪美新材料科技有限公司,广东 肇庆 526238
- 3. 广州高缇雅精细化工有限公司,广东 广州 528200
- 折叠
摘要
Abstract
The skin serves as a multifaceted barrier with numerous biological functions,and the presence of skin microbiota is integral to its overall functionality.Increasingly,the bacteria residing on the skin are acknowledged for their positive impact on human health.Staphylococcus epidermidis,the predominant colonizing bacteria on human skin,demonstrates remarkable resilience on normal skin surfaces due to its adept environmental adaptation,surface adhesion capabilities,and its role in maintaining cutaneous homeostasis and immune function.When skin health is compromised,Staphylococcus epidermidis demonstrates beneficial effects by exhibiting anti-inflammatory properties,promoting collagen synthesis,replenishing ceramide levels in the skin through sphingosphydase secretion,enhancing the tight junctions of keratinocytes to maintain skin barrier homeostasis,and interacting with host cells to preserve skin integrity.Furthermore,Staphylococcus epidermidis mitigates UV radiation damage by producing cytokines such as lipoteichoic acid or 6-HAP.Staphylococcus epidermidis and its metabolites have the potential to be utilized topically for skin improvement,either in their natural form or through genetic manipulation to enhance their beneficial properties.Cosmetic companies may explore the integration of these bacteria and their metabolites into skincare formulations to enhance skin health and preserve the skin's microecological equilibrium,potentially offering personalized skincare solutions utilizing the consumers'own Staphylococcus epidermidis.关键词
表皮葡萄球菌/化妆品/功效/共生菌Key words
Staphylococcus epidermidis/cosmetics/efficacy/symbiotic strains分类
化学化工引用本文复制引用
文霞,冯静,刘静霞,徐健,陈相孩,谢小保..表皮葡萄球菌应用于化妆品的研究进展[J].日用化学工业（中英文）,2025,55(1):89-97,9.
