日用化学工业（中英文）2025，Vol.55Issue(1)：98-103,6.DOI:10.3969/j.issn.2097-2806.2025.01.012
ICP-MS/MS法测定儿童彩妆类化妆品中的7种元素
Determination of 7 elements in children's makeup by ICP-MS/MS
摘要
Abstract
A method for the determination of 7 elements in children's makeup by inductively coupled plasma tandem mass spectrometry(ICP-MS/MS)was established.The sample was destroyed by a digestion acid system of nitric acid-hydrofluoric acid and digested by a super microwave digestion method.ICP-MS/MS was used to simultaneously determine the contents of 7 elements in children's cosmetics,including boron(B),titanium(Ti),germanium(Ge),molybdenum(Mo),tin(Sn),antimony(Sb),and tellurium(Te).Rhodium(Rh)was selected as the internal standard and an internal standard method was used for quantitative analysis.Methodological studies were conducted using cream-based,powder-based and lipstick-based cosmetic as matrices.The results show that 7 elements have good linear relationship within their respective mass concentration ranges,with correlation coefficients greater than 0.996 7.At the two spiked levels,the average recoveries in three matrices are 81.1%-104.6%,84.0%-116.0%,and 80.8%-113.1%,respectively,and the average relative standard deviations are 2.2%-7.5%,0.5%-7.1%,and 0.8%-7.3%,respectively.This method uses a digestion acid system of nitric acid-hydrofluoric acid and a super microwave digestion method for sample pretreatment.And ICP-MS/MS technology is applied to determine the contents of elements in children's cosmetics,solving the problem of element detection in different types of samples,especially those with complex composition and large matrix interference.It provides new ideas for sample pretreatment and element analysis of various cosmetics,filling the gap of 7 elements detection methods that have not yet been established in the existing legal standards.关键词
电感耦合等离子体串联质谱法(ICP-MS/MS)/超级微波消解/氢氟酸/儿童彩妆/元素分析Key words
ICP-MS/MS/super microwave digestion/hydrofluoric acid/children's makeup/elemental analysis分类
化学化工引用本文复制引用
吴莉,庞庆林,张妤琳,耿悦,陈民辉..ICP-MS/MS法测定儿童彩妆类化妆品中的7种元素[J].日用化学工业（中英文）,2025,55(1):98-103,6.基金项目
江苏省药品监督管理局科研计划项目(202211) （202211）
