上海针灸杂志2025，Vol.44Issue(1)：105-109,5.DOI:10.13460/j.issn.1005-0957.2025.01.0105
针刺联合坐位调膝法对退行性膝关节炎患者中医证候积分和膝关节活动度的影响
Effect of acupuncture plus sitting-position knee adjustment on the TCM symptom score and knee range of motion in patients with degenerative knee arthritis
摘要
Abstract
Objective To observe the effect of acupuncture plus sitting-position knee adjustment on the TCM symptom score and knee range of motion in patients with degenerative knee arthritis.Methods One hundred patients with degenerative knee arthritis were randomized to observation and control groups,with 50 cases in each group.The control group received sitting-position knee adjustment and the observation group,acupuncture at exercise acupoints in addition.The TCM symptom score,degenerative change indicators[matrix metalloproteinase-9(MMP-9),matrix metalloproteinase-1(MMP-1),cathepsin D(CAT-D)and tissue inhibitor of matrix metalloproteinase-1(TIMP-1)],serum inflammatory factors[interleukin-1(IL-1),tumor necrosis factor-α(TNF-α)and interleukin-6(IL-6)],the visual analog scale(VAS)score and knee joint function[the Lysholm knee score scale(LKSS)score and maximum knee range of motion]were observed in the two groups before and after treatment.Results After treatment,the joint swelling,joint range of motion and perigenual tenderness scores decreased significantly in the two groups(P＜0.05)and were lower in the observation group than in the control group(P＜0.05).After treatment,serum MMP-9,MMP-1,CAT-D and TIMP-1 decreased significantly in the two groups(P＜0.05)and were lower in the observation group than in the control group(P＜0.05).After treatment,serum IL-1,TNF-α and IL-6 levels decreased in the two groups compared with before and were lower in the observation group than in the control group(P＜0.05).After treatment,the VAS score decreased significantly and the knee range of motion and the LKSS score increased in the two groups(P＜0.05)and the VAS score was lower and the knee range of motion and the LKSS score were higher in the observation group than in the control group(P＜0.05).Conclusions Acupuncture plus sitting-position knee adjustment can reduce inflammatory factors levels and pain severity in patients with degenerative knee arthritis,improve knee function and range of motion and decrease the degree of degenerative change.关键词
针刺疗法/调膝法/骨关节炎,膝/膝关节活动度Key words
Acupuncture therapy/Knee adjustment/Osteoarthritis,Knee/Knee range of motion分类
医药卫生引用本文复制引用
丁成俊,张春健,韦镇余,胡舒然..针刺联合坐位调膝法对退行性膝关节炎患者中医证候积分和膝关节活动度的影响[J].上海针灸杂志,2025,44(1):105-109,5.基金项目
江苏省中医临床优秀人才研修项目[苏中医科教(2022)1号] （2022）
