四川医学2024，Vol.45Issue(12)：1303-1309,7.DOI:10.16252/j.cnki.issn1004-0501-2024.12.002
慢性阻塞性肺疾病急性加重期体外膈肌起搏治疗的Meta分析:疗效与安全性评估
Efficacy and Safety of External Diaphragm Pacing in the Treatment of Acute COPD:A Meta Analysis
摘要
Abstract
Objective To evaluate the efficacy and safety of external diaphragm pacing in patients with AECOPD by Meta analysis system,so as to provide evidence-based basis for clinical application.Methods Wanfang digital periodical full-text data-base,Chinese periodical full-text database,VIP Chinese sci-tech periodical database,PubMed,Web of Science,Embase,Cochrane Library,Chinese biomedical literature database were searched by computer.The search period was from the establishment of the da-tabase to July 1,2023.Randomized controlled trials of external diaphragm pacing on AECOPD were collected.Literature screening,data extraction and study bias risk assessment were conducted independently by two researchers,and RevMan5.3 software was used for Meta analysis.Results Total 1263 patients with 15 articles were included.Meta analysis showed that external diaphragm pa-cing could increase the indexes including PaO2,6min walking distance,reduce PCO2,and improve the pulmonary function indexes such as FEV1,FVC and FEV1/FVC.The differences were statistically significant.Conclusion Meta analysis shows that external diaphragm pacing can improve pulmonary function,increase PaO2,decrease PCO2 and improve the exercise ability in patients with AECOPD.关键词
体外膈肌起搏/慢性阻塞性肺疾病急性期/肺功能/生活质量Key words
extracorporeal diaphragm pacing/acute phase of COPD/pulmonary function/quality of life分类
医药卫生引用本文复制引用
肖洋,杨潇,李雪,张雨尧,雷宇,王永生..慢性阻塞性肺疾病急性加重期体外膈肌起搏治疗的Meta分析:疗效与安全性评估[J].四川医学,2024,45(12):1303-1309,7.基金项目
成都市科技项目(编号:2022-YF05-01368-SN) （编号:2022-YF05-01368-SN）
