实用医学杂志2025，Vol.41Issue(1)：1-6,6.DOI:10.3969/j.issn.1006-5725.2025.01.001
脂质组学在肾脏疾病中的应用与进展
Applications and advances of lipidomics in kidney disease
摘要
Abstract
Kidney disease constitutes a significant global public health issue,with its associated healthcare burden escalating annually.Lipid metabolism disorders play a crucial role in the onset and progression of various kidney diseases.Given the diversity of lipid species and the complexity of metabolic pathways,traditional research methods often fall short in fully elucidating the intricate roles of lipids in kidney diseases.In this context,lipido-mics,the systematic analysis of lipid molecules and their metabolic alterations in biological samples,emerges as a powerful tool with unique research value and clinical potential.This review summarizes the latest findings in lipido-mics across various kidney diseases and discusses the challenges encountered in clinical application and future research directions.关键词
糖尿病肾病/慢性肾脏病/急性肾损伤/脂质组学/生物标志物/发病机制Key words
diabetic nephropathy/chronic kidney disease/acute kidney injury/lipidomics/bio-markers/pathogenesis分类
医药卫生引用本文复制引用
王佳慧,郑可,李雪梅..脂质组学在肾脏疾病中的应用与进展[J].实用医学杂志,2025,41(1):1-6,6.基金项目
国家科技支撑计划项目(编号:2011BAI10B02) （编号:2011BAI10B02）
中央高水平医院临床科研业务费项目(编号:2022-PUMCH-A-172) （编号:2022-PUMCH-A-172）
北京市自然科学基金项目(编号:7232128) （编号:7232128）
北京市科技计划项目(编号:D181100000118001) （编号:D181100000118001）
