中国肺癌杂志2024，Vol.27Issue(11)：864-872,9.DOI:10.3779/j.issn.1009-3419.2024.101.30
纳米药物递送技术在克服肺癌耐药性中的应用
Application of Nano-drug Delivery Technology in Overcoming Drug Resistance in Lung Cancer
鲁迎春 1王春语 2柳斌3
作者信息
- 1. 610054 成都,电子科技大学医学院
- 2. 610032 成都,成都中医药大学医学与生命科学学院
- 3. 610042 成都,四川省肿瘤临床医学研究中心/四川省肿瘤医院·研究所/四川省癌症防治中心/电子科技大学附属肿瘤医院肿瘤内科
- 折叠
摘要
Abstract
Lung cancer is one of the most malignant tumor,representing a significant threat to human health.In China,its mortality rate is the highest among all malignant tumors.The occurrence of drug resistance has resulted in unfavour-able prognosis for patients with lung cancer,and overcoming drug resistance is a significant challenge that needs to be ad-dressed.Nano-drug delivery technology has been an important approach to overcome drug resistance in lung cancer.Targeting to the mechanisms of drug resistance,by enabling the combined delivery of drugs,increasing the efficiency of drug delivery and improving the targeting and safety of drugs,nano-drug delivery technology offers a novel approach to tackling drug resistance in lung cancer.This paper describes the current status of lung cancer treatment,mechanisms of drug resistance,strategies to overcome drug resistance,and the application of nanotechnology in the diagnosis and treatment of lung cancer.In addition,it summarizes the recent research progress on the application of nano-drug delivery technology to overcome drug resistance in lung cancer.Finally,the current prospects and challenges of nano-drug delivery technology are discussed.关键词
肺肿瘤/纳米药物递送技术/耐药Key words
Lung neoplasms/Nano-drug delivery technology/Drug resistance引用本文复制引用
鲁迎春,王春语,柳斌..纳米药物递送技术在克服肺癌耐药性中的应用[J].中国肺癌杂志,2024,27(11):864-872,9.
