中国全科医学2025,Vol.28Issue(9):1033-1043,11.DOI:10.12114/j.issn.1007-9572.2024.0514
基于药代动力学的临床常见药物急性中毒血液净化治疗共识
Consensus for Blood Purification Therapy Based on Pharmacokinetics in Acute Poisoning from Commonly Used Clinical Drugs
潘龙飞 1马青变 1朱华栋 1张国强 1马岳峰 1裴红红1
作者信息
摘要
Abstract
The incidence of acute poisoning caused by commonly used clinical drugs has been increasing annually,yet specific antidotes are lacking for most drug poisonings.Blood purification plays a crucial role in the treatment of acute poisoning.However,there are currently no unified recommendations in China regarding its application in cases of acute poisoning from commonly used clinical drugs.This consensus centers on pharmacokinetics,summarizing and outlining the strategies for applying blood purification in the treatment of acute poisoning caused by these drugs.Its aim is to assist clinicians in improving their understanding of pharmacokinetic parameters and the corresponding blood purification methods,so that they can select the appropriate blood purification technique and develop suitable treatment plans based on the pharmacokinetic characteristics of the drug involved.Ultimately,this seeks to improve outcomes in treating patients with acute poisoning from commonly used clinical drugs.关键词
中毒/药物过量/药代动力学/连续性肾替代疗法/急性中毒/药物中毒/血液净化Key words
Poisoning/Drug overdose/Pharmacokinetics/Continuous renal replacement therapy/Acute poisoning/Drug poisoning/Blood purification分类
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潘龙飞,马青变,朱华栋,张国强,马岳峰,裴红红..基于药代动力学的临床常见药物急性中毒血液净化治疗共识[J].中国全科医学,2025,28(9):1033-1043,11.