中国斜视与小儿眼科杂志2024，Vol.32Issue(4)：14-18,5.DOI:10.3969/J.ISSN.1005-328X.2024.04.004
儿童青少年近视重复照射低强度单波长红光对干眼影响的临床研究
Clinical study on the effect of repeated low intensity single wave length red light on dry eyes in children and ado-lescents with myopia
摘要
Abstract
Objective To investigate whether repeated exposure to low-intensity single wave length red light causes dry eye in children and adolescents with myopia.Method 50 children and adolescents(50 eyes)with myopia who received treatment at Shapingba Hospital affiliated with Chongqing University were enrolled as the research subjects.They were divided into an experimental group and a control group based on whether they received red light treatment,with 25 cases(25 eyes)in each group.The control group was treated with frame glasses.The experimental group received low-intensity single wave length red light treatment while wearing glasses.Before and after 3 months of treatment,inter group comparisons were made on the ocular surface disease index(OSDI),tear film break-up time(BUT),Schirmer I test(SIT),and the levels of inflammatory factors TNF-α,IL-6,IL-17,IL-1 β,IL-8,IL-1RA,and EGF in the two groups.And compare the above indicators within the experimental group before and after treatment to evaluate the effect of red light on dry eye in myopic children.Result There were no statistically significant differences(P＞0.05)in OSDI scores,BUT,SIT,and tear inflammatory factor levels between the experimental group and the control group before and after 3 months of treatment.After 3 months of red light treatment,the OSDI score of the experimental group patients increased compared to before treatment(P＜0.05),but the score was still less than 12 points,which was within the normal range.There were no statistically significant differences(P＞0.05)in the levels of TNF-α,IL-6,IL-17,IL-1 β,IL-8,IL-1RA,and EGF in the tears of the experimental group after treatment compared to baseline.Conclusion Repeated exposure to low-intensity single wave length red light for myopia in children and adolescents does not cause changes in ocular surface symptoms and signs,and can maintain the stability of ocular surface structure.It has high safety and can be recommended for myopia prevention and treatment.关键词
低强度红光/青少年/近视/干眼/泪液炎性因子Key words
Low-intensity red light/Teenagers/Myopia/Dry eyes/Inflammatory factors in tears引用本文复制引用
颜月,张灵丽,张娇,张聪..儿童青少年近视重复照射低强度单波长红光对干眼影响的临床研究[J].中国斜视与小儿眼科杂志,2024,32(4):14-18,5.基金项目
重庆市沙坪坝区科卫联合医学科研项目(2022SQKWLH013) （2022SQKWLH013）
