中国斜视与小儿眼科杂志2024,Vol.32Issue(4):21-23,后插4,4.DOI:10.3969/J.ISSN.1005-328X.2024.04.006
早产儿合并白化病的眼底血管发育特点分析
Characterization of fundus vascular development in premature infants with albinism
王建仓 1杜非凡 1杨晓格 1郭熙婷 1姜娇 1王韶奕 1魏云硕1
作者信息
- 1. 050000 河北省儿童医院眼科,河北省早产儿视网膜病变筛查中心
- 折叠
摘要
Abstract
Objective To characterize the development of fundus vasculature in preterm infants with albinism(ALB).Methods From October 2007 to January 2023,41(82 eyes)of 12876 premature infants who underwent retinopathy of prematurity(ROP)screening at the Children's Hospital of Hebei Province were included in the study.The general conditions,fundus manifestations and laboratory test results of the children were collected and analyzed.Results Among the 41 ALB infants,28(56 eyes)were male and 13(26 eyes)were female,with a mean gestation age of 32.80±1.86(28~36)weeks and mean birth weight of 1847.80±390.68(910~2710)grams.Thirty-four children had oculocutaneous ALB,6 had ocular ALB,and 1 had ALB-related syndrome.All infants had fully developed fundus vascula-ture at the corrected gestational age of 38 weeks,and two infants had stage 1 ROP.Conclusions The incidence of ROP is lower in preterm infants with ALB under the same influencing factors.Retinal pigment epithelial detachment reduces the pro-duction of vascular endothelial growth factor,which in turn lowers the risk of proliferative vascular lesions in the fundus.关键词
早产儿/白化病/早产儿视网膜病变/眼底血管增殖性病变Key words
Premature infant/Albinism/Retinopathy of prematurity/Proliferative vascular disease of fundus引用本文复制引用
王建仓,杜非凡,杨晓格,郭熙婷,姜娇,王韶奕,魏云硕..早产儿合并白化病的眼底血管发育特点分析[J].中国斜视与小儿眼科杂志,2024,32(4):21-23,后插4,4.