转化医学杂志2024，Vol.13Issue(8)：1156-1159,1188,5.DOI:10.3969/j.issn.2095-3097.2024.08.003
低碳水化合物饮食对肥胖型多囊卵巢综合征患者代谢、内分泌指标和妊娠结局的影响
The Impact of Low-Carbohydrate Diet on Endocrine and Pregnancy Out-comes in Obesity Patients with PCOS
摘要
Abstract
Objective To investigate the effects of low-carbohydrate diet on metabolic indexes,endocrine indexes and pregnancy outcomes in obese patients with polycystic ovary syndrome(PCOS).Methods A total of 218 obese PCOS pa-tients admitted from February 2021 to June 2023 were divided into experimental group(n=109)and control group(n=109)by random number table method.The experimental group was given a low-carbohydrate diet and the control group was given a conventional diet for 8 weeks.The basic indexes,metabolic and endocrine indexes of the two groups were compared before and after the intervention of low-carbohydrate diet,and the pregnancy outcomes of the two groups were followed up.Results Be-fore low-carbohydrate diet intervention,there were no significant differences in age,body mass index(BMI),body fat per-centage,waist-to-hip ratio,triglyceride(TG),fasting insulin(FINS),aspartate aminotransferase(AST),alanine amin-otransferase(ALT)and uric acid(UA)between 2 groups(P＞0.05).After low-carbohydrate diet intervention,BMI,body fat percentage,waist-to-hip ratio,TG,FINS,AST,ALT and UA in test group were significantly lower than those in control group(P＜0.05).The total pregnancy rate in the experimental group was significantly higher than that in the control group(P＜0.05).Conclusion Low carbohydrate diet intervention for obese PCOS patients can effectively reduce body mass relat-ed indexes,improve metabolic and endocrine indexes,and increase pregnancy rate.关键词
多囊卵巢综合征/低碳水化合物饮食/肥胖/三酰甘油/空腹胰岛素/天冬氨酸转氨酶/丙氨酸转氨酶/尿酸Key words
Polycystic ovary syndrome/Low-carbohydrate diet/Obesity/Triglyceride/Fasting insulin/Aspartate aminotransferase/Alanine aminotransferase/Uric acid分类
医药卫生引用本文复制引用
高原,高杨,管桂雪,孙倩,徐金金,杨文..低碳水化合物饮食对肥胖型多囊卵巢综合征患者代谢、内分泌指标和妊娠结局的影响[J].转化医学杂志,2024,13(8):1156-1159,1188,5.基金项目
连云港市妇幼健康科研项目(F202103) （F202103）
江苏省妇幼健康科研项目(F202317) （F202317）
